Microbial resistance to prophylactic drugs: nitrofurantoin (1) versus cotrimoxazole (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 probably leads to lower microbial resistance to prophylactic drugs: nitrofurantoin (1)… compared with antibiotic 2 (moderate certainty).
1 finding from 1 review
Adverse events: cotrimoxazole (1) versus cefprozil (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 showed no clear difference in adverse events: cotrimoxazole (1) versus cefprozil (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Adverse events: nitrofurantoin (1) versus trimethoprim (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 may leads to higher adverse events: nitrofurantoin (1) versus trimethoprim (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children without VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children without VUR compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children with VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children with VUR compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children, in studies with adequate allocation concealment · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment probably leads to lower recurrence of symptomatic UTI in children, in studies with adequate… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Repeat positive urine culture · children with previous UTI and most do not have a renal tract abnormality such as VUR
It is very uncertain whether antibiotic treatment changes repeat positive urine culture compared with placebo or no treatment (very low certainty).
1 finding from 1 review
All adverse events · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in all adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
Microbial resistance to prophylactic drug · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in microbial resistance to prophylactic drug compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 showed no clear difference in recurrence of symptomatic UTI: cotrimoxazole (1) versus cefadroxil (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Intervention not reported
Number of subjects who developed symptomatic UTI (6 months to 1 year) · adults with asymptomatic bacteriuria
The intervention showed no clear difference in number of subjects who developed symptomatic UTI (6 months to 1 year) (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of subjects who developed complications (10 months to 3 years) · adults with asymptomatic bacteriuria
The intervention showed no clear difference in number of subjects who developed complications (10 months to 3 years) (moderate certainty).
1 finding from 1 review
Intervention not reported
Death (6 months to 8 years) · adults with asymptomatic bacteriuria
The intervention showed no clear difference in death (6 months to 8 years) (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of subjects who develop any adverse event (42 days to 10 months) · adults with asymptomatic bacteriuria
The intervention probably leads to higher number of subjects who develop any adverse event (42 days to 10… (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of subjects with bacteriological cure (42 days to 4 years) · adults with asymptomatic bacteriuria
The intervention probably leads to higher number of subjects with bacteriological cure (42 days to 4 years) (moderate certainty).
1 finding from 1 review
Fever clearance time · children with acute pyelonephritis
1 finding from 1 review
Increase in serum creatinine during treatment · children with acute pyelonephritis
Different dosing regimens of aminoglycosides (daily showed no clear difference in increase in serum creatinine during treatment compared with 8 hourly) (low certainty).
1 finding from 1 review
Persistent bacteriuria · children with acute pyelonephritis
Agent: Third generation cephalosporin showed no clear difference in persistent bacteriuria compared with other antibiotic (low certainty).
1 finding from 1 review
Recurrent UTI after end of therapy · children with acute pyelonephritis
Agent: Third generation cephalosporin showed no clear difference in recurrent UTI after end of therapy compared with other antibiotic (low certainty).
1 finding from 1 review
Persistent symptoms · children with acute pyelonephritis
Agent: Third generation cephalosporin may leads to lower persistent symptoms after end of treatment compared with other antibiotic (low certainty).
1 finding from 1 review