Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

170 questions · 173 findings · 19 reviews · Pregnancy and Childbirth

No studies found 20 · 11.6%GRADE not reported 43 · 24.9%Very low 46 · 26.6%Low 40 · 23.1%Moderate 14 · 8.1%High 10 · 5.8%

Single‐dose antibiotic vs short duration antibiotics

Recurrent asymptomatic bacteriuria ‐ all trials · patients with asymptomatic bacteriuria during pregnancy

It is very uncertain whether single‐dose antibiotic changes recurrent asymptomatic bacteriuria ‐ all trials compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Pyelonephritis ‐ Same antimicrobial agent only4 · patients with asymptomatic bacteriuria during pregnancy

It is very uncertain whether single‐dose antibiotic changes pyelonephritis ‐ Same antimicrobial agent only4 compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Low birthweight ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic leads to higher low birthweight ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Preterm delivery ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic showed no clear difference in preterm delivery ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (moderate certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Same antimicrobial agent ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic leads to higher same antimicrobial agent ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Different antimicrobial agents ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic showed no clear difference in different antimicrobial agents ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (low certainty).

1 finding from 1 review

Antibiotic prophylaxis vs no treatment

Incidence of episiotomy wound dehiscence without wound infection · women with episiotomy repair following vaginal birth

It is very uncertain whether antibiotic prophylaxis changes incidence of episiotomy wound dehiscence without wound infection compared with no treatment (very low certainty).

1 finding from 1 review