Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

186 questions · 190 findings · 36 reviews

No studies found 38 · 20%GRADE not reported 75 · 39.5%Very low 42 · 22.1%Low 20 · 10.5%Moderate 14 · 7.4%High 1 · 0.5%

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Side effects / tolerability · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings ‐ Erector spinae plane block vs serratus anterior plane block

Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia

Summary of findings ‐ Erector spinae plane block showed no clear difference in rates of block‐related adverse events compared with serratus anterior plane block (low certainty).

1 finding from 1 review

Metal-free single crowns (full-contour zirconia) vs Composite strip crown

Treatment failure (annual failure rate) · Children (aged 3-5.5 years) with early childhood caries in anterior primary teeth (>=2 carious surfaces), no pulp therapy

Zirconia crowns failed less than composite strip crowns (3.3% vs 15% annual failure) in one RCT; low quality of evidence (ungraded).

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Bleeding, as measured by: amount of blood loss; complete cessation of bleeding as assessed clinically by the investigator; time required for the control of bleeding · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

R-appliance vs Anterior inclined bite plate (AIBP)

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

R-appliance showed no clear difference in final ANB compared with anterior inclined bite plate (AIBP); GRADE not reported.

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Discomfort associated with the procedure · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Adverse events · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Costs: direct cost of treatment · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Inferior oblique disinsertion vs anterior transposition

Proportion of participants who received additional strabismus surgery · people with unilateral superior oblique palsy

It is very uncertain whether inferior oblique disinsertion changes proportion of participants who received additional strabismus surgery compared with anterior transposition (very low certainty).

1 finding from 1 review