Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
G-CSF led to lower oral mucositis (severe) compared with placebo/no treatment; GRADE not reported.
1 finding from 1 review
RR 0.36 [0.15, 0.86]
2 studies
GRADE not reported
Length of hospital stay · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
The review found no eligible studies for this question.
1 finding from 1 review
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Mixed beam (neutron and photon) radiotherapy showed no clear difference in locoregional control compared with conventional photon radiotherapy; GRADE not reported.
1 finding from 1 review
Daily mean opiate intake per hour · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Hypnosis showed no clear difference in daily mean opiate intake per hour compared with control (treatment as usual); GRADE not reported.
1 finding from 1 review
Mucositis severity (mild to moderate) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
1 finding from 1 review
Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Hypnosis showed no clear difference in average pain scores (0-100 VAS) compared with control (treatment as usual); GRADE not reported.
1 finding from 1 review
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Hyperfractionated/accelerated radiotherapy led to lower locoregional control compared with conventional (standard) fractionation radiotherapy; GRADE not reported.
2 findings from 1 review
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
1 finding from 1 review
Daily mean opiate intake per hour · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Patient-controlled analgesia (PCA) pethidine showed no clear difference in daily mean opiate intake per hour compared with staff-controlled delivery of pethidine; GRADE not reported.
1 finding from 1 review
Mucositis eradicated · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Sucralfate showed no clear difference in mucositis eradicated compared with placebo; GRADE not reported.
1 finding from 1 review
Mucositis eradicated · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Chlorhexidine mouthwash showed no clear difference in mucositis eradicated compared with salt and soda mouthwash; GRADE not reported.
1 finding from 1 review
Mycological: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
Fluconazole (absorbed from GI tract) showed no clear difference in mycological: eradication of oral candidiasis compared with ketoconazole (absorbed from GI tract); GRADE not reported.
1 finding from 1 review
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Low dose rate interstitial radiotherapy showed no clear difference in locoregional control compared with high dose rate interstitial radiotherapy; GRADE not reported.
1 finding from 1 review
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
1 finding from 1 review
Hyperfractionated/accelerated split course vs accelerated boost (Fu 1995, feasibility study, 75 participants): authors report no significant difference in total mortality; data not presented in a way that allows…
1 study · 75 participants
GRADE not reported
Clinical: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
Miconazole 50 mg tablet (partially absorbed) showed no clear difference in clinical: eradication of oral candidiasis compared with miconazole 500 mg gel (partially absorbed); GRADE not reported.
1 finding from 1 review
Clinical: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
Fluconazole (absorbed from GI tract) showed no clear difference in clinical: eradication of oral candidiasis compared with itraconazole (absorbed from GI tract); GRADE not reported.
1 finding from 1 review
Cost of oral care · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
The review found no eligible studies for this question.
1 finding from 1 review
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found
Quality of life · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Phenytoin mouthrinse led to lower quality of life compared with placebo; GRADE not reported.
1 finding from 1 review
Disease-free survival · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Altered fractionation radiotherapy (hyperfractionated and/or… showed no clear difference in disease free survival compared with conventional (standard) fractionation radiotherapy; GRADE not reported.
2 findings from 1 review
Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Diclofenac showed no clear difference in average pain scores (0-100 VAS) compared with placebo; GRADE not reported.
1 finding from 1 review