Question · asked by 1 review
Phenytoin mouthrinse vs placebo: Quality of life
- Population
- People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
- Intervention
- Phenytoin mouthrinse
- Comparison
- placebo
- Outcome
- Quality of life
Phenytoin mouthrinse led to lower quality of life compared with placebo; GRADE not reported.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Phenytoin mouthrinse vs Placebo Quality of life · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis · 7 days Phenytoin mouthrinse led to lower quality of life compared with placebo; GRADE not reported. Interventions for treating oral mucositis for patients with cancer receiving treatment (2010) · Cochrane All outcomes | MD -15.10 [-26.04, -4.16] | 1 study · 12 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for treating oral mucositis for patients with cancer receiving treatment 2010 · Cochrane All outcomes | 2010-06 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.