Serious adverse events (n/N)
Summary of findings: insulin detemir showed no clear difference in serious adverse events (n/N) compared with NPH insulin (moderate certainty).
1 finding from 1 review
HbA1c (%)
FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis
The review found no eligible studies for this question.
2 findings from 1 review
Quality of life · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in BMI · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to next exacerbation · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · adults and children with cystic fibrosis
1 finding from 1 review
Change in dystonia from baseline Measured by: BADS (eight body regions assessed for dystonia on a five‐point scale (0 = none to 4 = severe), minimum score 0 to maximum score 32; higher score = greater severity of dystonia) · children with dystonic cerebral palsy
1 finding from 1 review
no estimate extracted
16 participants
Low
Adverse effectsb (mood disturbance, irritability, behavioural change, constipation) Measured by: counts of number and type · children with dystonic cerebral palsy
Summary of findings: Trihexyphenidyl may leads to higher adverse effectsb (mood disturbance, irritability, behavioural… compared with placebo (low certainty).
1 finding from 1 review
RR 2.54 [1.38, 4.67]
16 participants
Low
Participation in activities of daily living:individual goal setting Measured by: GAS (up to 5 functional goals scored on a 5‐point scale (−2 = much less than expected to +2 = much more than expected); higher score = better than expected outcome) · children with dystonic cerebral palsy
1 finding from 1 review
no estimate extracted
16 participants
Low
Participation in activities of daily living:satisfaction with individual goals Measured by: satisfaction subscale of the COPM (satisfaction with performance in up to 5 problem areas scored on a 10‐point scale (1 = not satisfied at all to 10 = extr... · children with dystonic cerebral palsy
1 finding from 1 review
no estimate extracted
16 participants
Low
Participation in activities of daily living:performance of individual goals Measured by: performance subscale of the COPM (up to five problem areas scored on a 10‐point scale (1 = not able to do to 10 = able to do extremely well; higher score = be... · children with dystonic cerebral palsy
1 finding from 1 review
no estimate extracted
16 participants
Low
Quality of life · children with dystonic cerebral palsy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean GI symptom scores · Men undergoing RT for prostate cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acute and late GI toxicity (grade 2+) · Men undergoing RT for prostate cancer
Summary of findings: Hydrogel spacer showed no clear difference in acute and late GI toxicity (grade 2+) compared with no intervention (low certainty).
1 finding from 1 review
Diarrhoea (grade 2+) · Men undergoing RT for prostate cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
QoL · Men undergoing RT for prostate cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean GI symptom scores · Men with prostate cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acute and late GI toxicity (grade 2+) · Men with prostate cancer
It is very uncertain whether summary of findings: Corticosteroids changes acute and late GI toxicity (grade 2+) compared with placebo (very low certainty).
1 finding from 1 review
Diarrhoea (grade 2+) · Men with prostate cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found