What do systematic reviews say?

Any early psychological intervention vs active control

• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 239 participants
  Low

Any early psychological intervention vs inactive control (usual care care, attention control, waitlist)

Any early psychological intervention may leads to lower PTSD diagnosis: 3–6 months compared with waiting list/usual care (low certainty).

• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  RR 0.62 [0.41, 0.93]
  5 studies · 758 participants
  Low
• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  RR 0.94 [0.2, 4.49]
  1 study · 132 participants
  Very low

Any early psychological intervention vs inactive control (usual care care, attention control, waitlist)

Any early psychological intervention showed no clear difference in dropouts from treatment compared with waiting list/usual care (low certainty).

• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  RR 1.34 [0.91, 1.95]
  11 studies · 1154 participants
  Low

Any early psychological intervention vs inactive control (usual care care, attention control, waitlist)

• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  no estimate extracted
  15 studies · 1921 participants
  Low

Any early psychological intervention vs inactive control (usual care care, attention control, waitlist)

• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 1009 participants
  Low

Any early psychological intervention vs inactive control (usual care care, attention control, waitlist)

• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 945 participants
  Low

Any early psychological intervention vs active control

Any early psychological intervention may leads to higher dropouts from treatment compared with active control condition (low certainty).

• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  RR 1.61 [1.11, 2.34]
  2 studies · 425 participants
  Low

Any early psychological intervention vs active control

• Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 465 participants
  Low

Intervention not reported

The intervention may leads to lower anaemia Defined as haemoglobin (Hb) concentration < 11 g/dL Measured… (low certainty).

• Food fortification with multiple micronutrients: impact on health outcomes in general population 2019 · Cochrane Headline outcomes only
  RR 0.68 [0.56, 0.84]
  11 studies · 3746 participants
  Low

Intervention not reported

The intervention may leads to lower micronutrient deficiencies (low certainty).

• Food fortification with multiple micronutrients: impact on health outcomes in general population 2019 · Cochrane Headline outcomes only
  RR 0.44 [0.32, 0.6]
  11 studies · 3289 participants
  Low

Intervention not reported

• Food fortification with multiple micronutrients: impact on health outcomes in general population 2019 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 2889 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes anaemia Anaemia was defined as a haemoglobin (Hb) concentration < 13… (very low certainty).

• Food fortification with multiple micronutrients: impact on health outcomes in general population 2019 · Cochrane Headline outcomes only
  RR 0.86 [0.37, 2.01]
  1 study · 88 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes micronutrient deficiencies (very low certainty).

• Food fortification with multiple micronutrients: impact on health outcomes in general population 2019 · Cochrane Headline outcomes only
  RR 0.98 [0.82, 1.17]
  1 study · 88 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Food fortification with multiple micronutrients: impact on health outcomes in general population 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

ADMG + CAF vs CAF

• Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes

  Short term (6 to 12 months)
  Ahmedbeyli 2014: patients rated ADMG + CAF and CAF equally for pain during surgery, discomfort, postsurgical pain/swelling and complications
  1 study
  GRADE not reported

GTR rm + CAF vs SCTG + CAF

• Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes

  Short term (6 to 12 months)
  Wang 2001: two patients treated with SCTG experienced adverse effects (one postsurgical swelling, one postsurgical ecchymosis)
  1 study
  GRADE not reported

GTR rm + CAF vs GTR nrm + CAF

GTR rm + CAF showed no clear difference in clinical attachment level change compared with GTR nrm + CAF; GRADE not reported.

• Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes

  Short term (6 to 12 months)
  MD 0.12 [-0.37, 0.60]
  2 studies
  GRADE not reported

EMP + CAF vs CAF

• Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
  Sangiorgio 2017 (VAS): root coverage aesthetics and overall aesthetic results showed similar/equivalent outcomes for EMP + CAF and CAF
  1 study
  GRADE not reported

GTR rm associated with bone substitutes + CAF vs GTR rm + CAF

GTR rm associated with bone substitutes + CAF showed no clear difference in keratinized tissue width change compared with GTR rm + CAF; GRADE not reported.

• Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes

  Short term (6 to 12 months)
  MD 0.23 [-0.21, 0.68]
  2 studies
  GRADE not reported

XCM + CAF vs CAF

• Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
  Sangiorgio 2017 (VAS): root coverage aesthetics and overall aesthetic results were similar for XCM + CAF and CAF, irrespective of the treatment applied
  1 study
  Low