Miscarriage · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in miscarriage (All) compared with no intervention, placebo or other micronutrients without folate… (moderate certainty).
1 finding from 1 review
Cleft lip (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in cleft lip (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Cleft palate (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in cleft palate (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Congenital cardiovascular anomalies (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in congenital cardiovascular anomalies (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Other congenital anomalies (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in other congenital anomalies (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Neonatal mortality · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Maternal anaemia at or near term (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Maternal red blood cell folate at or near term (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Serum folate at or near term · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Intervention not reported
All‐cause death · patients with neovascular age‐related macular degeneration
The intervention showed no clear difference in all‐cause death (moderate certainty).
1 finding from 1 review
Intervention not reported
All serious systemic adverse events · patients with neovascular age‐related macular degeneration
The intervention showed no clear difference in all serious systemic adverse events (low certainty).
1 finding from 1 review
Intervention not reported
Infection · patients with neovascular age‐related macular degeneration
The intervention showed no clear difference in infection (moderate certainty).
1 finding from 1 review
Intervention not reported
Arterial thromboembolic event · patients with neovascular age‐related macular degeneration
The intervention showed no clear difference in arterial thromboembolic event (moderate certainty).
1 finding from 1 review
Intervention not reported
Myocardial infarction · patients with neovascular age‐related macular degeneration
The intervention showed no clear difference in myocardial infarction (moderate certainty).
1 finding from 1 review
Intervention not reported
Stroke · patients with neovascular age‐related macular degeneration
The intervention showed no clear difference in stroke (moderate certainty).
1 finding from 1 review
Intervention not reported
Gastrointestinal disorders MedDRA class · patients with neovascular age‐related macular degeneration
The intervention probably leads to higher gastrointestinal disorders MedDRA class (moderate certainty).
1 finding from 1 review
Fatal and non‐fatal injuries in RCT, short‐term · firms potentially subject to inspection
Inspection showed no clear difference in fatal and non‐fatal injuries in RCT, short‐term compared with no intervention (low certainty).
1 finding from 1 review
RR 1.04 [0.9, 1.21]
Studies not reported
Low
Fatal and non‐fatal injuries in CBA, long‐term · firms potentially subject to inspection
Inspection showed no clear difference in fatal and non‐fatal injuries in CBA, medium‐term compared with no intervention (low certainty).
2 findings from 1 review
RR 0.87 [0.75, 1.02]
Studies not reported
Low
RR 0.77 [0.64, 0.92]
Studies not reported
Low
Fatal and non‐fatal crashes, ITS‐level Crash data · firms potentially subject to inspection
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Fatal and non‐fatal crashes, ITS‐slope Crash data · firms potentially subject to inspection
1 finding from 1 review
no estimate extracted
Studies not reported
Low