Bone pain · Adults with chronic kidney disease requiring dialysis
Meta-analysis of randomised trials of vitamin D supplementation for Bone pain: RR 0.29 (95% CI 0.03 to 2.63), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
Bone mineral density · Older or community-dwelling adults
Meta-analysis of randomised trials of vitamin D supplementation for Bone mineral density, Community-dwelling adults: WMD -0.9 (95% CI -2.10 to 0.40), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
WMD -0.9 [-2.10, 0.40]
3 studies
GRADE not reported
Dental caries · children
Meta-analysis of randomised trials of vitamin D supplementation for Dental caries: RR 0.53 (95% CI 0.43 to 0.65), statistically significant. Umbrella review outcome-level evidence grade: Probable.
1 finding from 1 review
Taste · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve
The review found no eligible studies for this question.
1 finding from 1 review
Thermosensory (thermal) perception · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve
Low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… showed no clear difference in thermosensory (thermal) perception compared with placebo (sham) laser therapy; GRADE not reported.
1 finding from 1 review
Insulin resistance · Adults with diabetes
Meta-analysis of randomised trials of vitamin D supplementation for Insulin resistance (Diabetes): SMD 0.16 (95% CI -0.11 to 0.42), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
SMD 0.16 [-0.11, 0.42]
5 studies
GRADE not reported
Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
The review found no eligible studies for this question.
1 finding from 1 review
Episode frequency associated with oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
Sucralfate suspension (topical) showed no clear difference in frequency of oral ulcers compared with placebo suspension; GRADE not reported.
1 finding from 1 review
Patient satisfaction · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve
The review found no eligible studies for this question.
1 finding from 1 review
Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review
Because of substantial clinical and methodological heterogeneity in the studies, we were unable to determine an estimate of effect
2 studies · 148 participants
Very low
Episode duration associated with oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
SoF (topical interventions vs placebo), grouped comment spanning all four listed outcomes (verbatim): "5 placebo-controlled trials evaluated topical interventions (sucralfate suspension (2 trials), interferon-alpha (2…
Studies not reported
GRADE not reported
Dry mouth (xerostomia) · Adults with dry mouth due to Sjogren's Syndrome
1 finding from 1 review
Proportion of children developing new caries (deciduous) · Children and adolescents aged 16 years or less
Fluoride varnish showed no clear difference in proportion of children developing one or more new caries… compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Oral health assessment · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Duration of effectiveness · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Oral health assessment · Adults with dry mouth due to Sjogren's Syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Quality of life · Adults with dry mouth due to Sjogren's Syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Adverse effects / specific side effects (oral allergic reactions, mucosal irritation, adverse symptoms such as nausea, gagging, vomiting) · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment in primary/deciduous teeth: decayed, (extraction indicated/missing) and filled teeth d(e/m)ft (prevented fraction) · Children and adolescents aged 16 years or less
1 finding from 1 review
Unstimulated whole saliva (UWS) · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
Acupuncture may leads to higher unstimulated whole saliva (UWS) compared with placebo (sham acupuncture) (low certainty).
2 findings from 1 review