Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,432 questions · 1,467 findings · 116 reviews · Headline outcomes only

No studies found 232 · 15.8%GRADE not reported 202 · 13.8%Very low 286 · 19.5%Low 327 · 22.3%Moderate 286 · 19.5%High 134 · 9.1%

HALOPERIDOL vs ANTIPSYCHOTIC & BENZODIAZEPINE ‐ HALOPERIDOL + MIDAZOLAM

Repeated need for tranquillisation ‐ not reported · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes repeated need for tranquillisation compared with COMBINATIONS: c. HALOPERIDOL + MIDAZOLAM (very low certainty).

1 finding from 1 review

HALOPERIDOL vs COMBINATIONS: c. HALOPERIDOL + PROMETHAZINE

Repeated need for tranquillisation ‐ not reported · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes repeated need for tranquillisation compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (very low certainty).

1 finding from 1 review