Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,438 questions · 1,463 findings · 125 reviews · Anaesthesia

No studies found 197 · 13.5%GRADE not reported 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Sugammadex 4.0 mg/kg vs neostigmine (any dose)

Risk of adverse events and serious adverse eventsb, bradycardia, PONV, and signs of residual neuromuscular blockade · Adult patients, ASA I‐IV, who received non‐depolarizing NMBAs

The review found no eligible studies for this question.

1 finding from 1 review

Sugammadex (any dose) vs neostigmine (any dose)

Risk of composite adverse eventsb · Adult patients, ASA I‐IV, who received non‐depolarizing NMBAs

Sugammadex (any dose) probably leads to lower risk of composite adverse eventsb compared with neostigmine (any dose) (moderate certainty).

1 finding from 1 review

Neuraxial vs general anaesthesia

Return of patient to their own home · Patients with hip fracture repair

It is very uncertain whether neuraxial block changes return of patient to their own home compared with general anaesthesia (very low certainty).

1 finding from 1 review

Advanced haemodynamic monitoring vs protocol using standard measures such

All‐cause mortality Advanced haemodynamic monitoring · patients with proximal femoral fracture

It is very uncertain whether advanced haemodynamic monitoring changes all‐cause mortality Advanced haemodynamic monitoring compared with protocol using standard measures such (very low certainty).

1 finding from 1 review