Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
There is no clear difference in WSL initiation between glass ionomer cement and resin adhesive for bracket bonding (RR 0.72, not significant); certainty of evidence is very low.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
Sealant use reduced the incidence of new white spot lesions versus no sealant (very low certainty).
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
For compomer-based bonding agents, fluoride release did not significantly change WSL initiation (RR 0.71); subgroup not separately GRADE-rated.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
Among non-fluoride sealants, WSL initiation was significantly reduced versus no sealant (RR 0.69); subgroup not separately GRADE-rated.
1 finding from 1 review
White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
White spot lesions were also measured by laser fluorescence in 3 sealant-vs-no-sealant studies, but no meta-analysis was possible due to incompatible reporting.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
Fluoride-releasing compomer bonding agent did not show a statistically significant reduction in new white spot lesions versus non-fluoride compomer bonding agent (very low certainty).
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
For resin-based sealants, fluoride release did not significantly change WSL initiation (RR 0.71, wide CI); subgroup not separately GRADE-rated.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
The additional use of a sealant probably reduces the initiation of white spot lesions during fixed orthodontic treatment compared with no sealant (RR 0.70), but the certainty of evidence is very low.
1 finding from 1 review
White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
White spot lesions were also measured by laser fluorescence in 3 fluoride-vs-non-fluoride studies, but no meta-analysis was possible due to incompatible reporting.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
Fluoride-releasing coating materials do not appear to reduce WSL initiation more than non-fluoride coatings (RR 0.84, not significant); certainty of evidence is very low.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
For resin-based bonding agents, fluoride release did not significantly change WSL initiation (RR 0.97); subgroup not separately GRADE-rated.
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Adjusted analyses also showed no association between low birth weight and early childhood caries (adjusted OR 1.05, 95% CI 0.71 to 1.57); certainty not graded.
3 findings from 1 review
Adverse effects (apart from fluorosis) · Pregnant women (for preventing dental caries in the primary teeth of their children)
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Filled primary surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)
Fluoride supplementation (tablets, drops, lozenges or chewing gum) showed no clear difference in filled primary surfaces at 5 years compared with placebo or no treatment; GRADE not reported.
2 findings from 1 review
Caries presence in primary teeth · Pregnant women (for preventing dental caries in the primary teeth of their children)
It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes children with caries in the primary teeth at 3 years compared with placebo or no treatment (very low certainty).
2 findings from 1 review
Fluorosis (maxillary teeth) at 5 years · Pregnant women (for preventing dental caries in the primary teeth of their children)
It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes fluorosis (maxillary teeth) at 5 years compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Caries in primary teeth: dmft (3 years) · Pregnant women (for preventing dental caries in the primary teeth of their children)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Missing primary surfaces (ms) · Pregnant women (for preventing dental caries in the primary teeth of their children)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fluorosis (mandibular teeth) at 5 years · Pregnant women (for preventing dental caries in the primary teeth of their children)
It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes fluorosis (mandibular teeth) at 5 years compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Decayed primary surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)
Fluoride supplementation (tablets, drops, lozenges or chewing gum) showed no clear difference in decayed primary surfaces at 3 years compared with placebo or no treatment; GRADE not reported.
2 findings from 1 review