Fracture · Participants in observational studies
The meta-analysis of observational studies reported a SMD (to OR) of 0.31 (95% CI 0.23 to 0.42) for higher versus lower circulating vitamin D concentration.
1 finding from 1 review
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
NobelActive internal connection implants led to lower marginal bone level change compared with nobel Speedy Groovy external connection implants; GRADE not reported.
1 finding from 1 review
Body‐mass index (BMI) · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Body mass index: Z score -0.15 (95% CI -0.19 to -0.11), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Sporadic colorectal adenoma · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Sporadic colorectal adenoma: OR 0.82 (95% CI 0.69 to 0.97), statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
NobelActive internal connection implants showed no clear difference in implant failure compared with nobelReplace implants; GRADE not reported.
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review
Primary pairwise data unusable (implant numbers per surface not disclosed); one turned implant failed early. Data used only for the turned-vs-roughened secondary analysis (Wennstrom 2004)
1 study · 51 participants
GRADE not reported
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
WINSIX cylindrical implants showed no clear difference in implant failure compared with WINSIX tapered implants; GRADE not reported.
1 finding from 1 review
Position of the incisors (upper incisor inclination) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
The author reported that data (1.NA, 1-NA, 1-PP, 1.NB, 1-NB, 1-GoMe) showed a statistically significant difference. There was palatal inclination of the upper incisors in the intervention group that contributed to…
1 study
GRADE not reported
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review
All cause mortality (in CKD patients) · Participants in observational studies
The meta-analysis of observational studies reported a RR of 0.88 (95% CI 0.81 to 0.93) for higher versus lower circulating vitamin D concentration.
1 finding from 1 review
Type 2 diabetes (prevalent) · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Type 2 diabetes (prevalent): OR 0.45 (95% CI 0.25 to 0.82), statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
Side effects / tolerability · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
The review found no eligible studies for this question.
1 finding from 1 review
Failure to correct the anterior open bite (open bite not closed) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
Removable appliance with palatal crib associated with high-pull… led to lower failure to correct the anterior open bite (open bite not closed) compared with no treatment; GRADE not reported.
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review
All cause mortality · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for All cause mortality: HR 0.72 (95% CI 0.66 to 0.78), statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review
Prosthesis failure · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus
Maxillary sinus lift (augmentation) with long implants showed no clear difference in prosthesis failure compared with short implants (5 to 8.5 mm) without sinus augmentation (moderate certainty).
1 finding from 1 review