Findings

What do systematic reviews say?

885 questions · 903 findings · 72 reviews

No studies found 106 · 11.7%GRADE not reported 45 · 5%Very low 114 · 12.6%Low 238 · 26.4%Moderate 314 · 34.8%High 86 · 9.5%

Hospital admissions · patients with adults with acute asthma

Aminophylline showed no clear difference in hospital admissions compared with placebo (moderate certainty).

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
OR 0.58 [0.3, 1.12]
6 studies · 315 participants
Moderate

Tremor · patients with adults with acute asthma

Aminophylline showed no clear difference in tremor compared with placebo (low certainty).

1 finding from 1 review

Vomiting · patients with adults with acute asthma

Aminophylline probably leads to higher vomiting compared with placebo (moderate certainty).

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
OR 4.21 [2.2, 8.07]
7 studies · 321 participants
Moderate

Arrhythmia/palpitations · patients with adults with acute asthma

Aminophylline probably leads to higher arrhythmia/palpitations compared with placebo (moderate certainty).

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
OR 3.02 [1.15, 7.9]
6 studies · 249 participants
Moderate

Convulsions · patients with adults with acute asthma

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Moderate