Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,097 questions · 3,266 findings · 631 reviews

No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

Home fall‐hazard reduction vs control (e.g. usual activities)

QoL · older people living in the community (included trials conducting pre‐ and/or post‐hospital discharge home visits focusing on fall…

Home fall‐hazard reduction showed no clear difference in health‐related quality of life SMD was calculated from 4 studies… compared with control (e.g. usual care) (moderate certainty).

1 finding from 1 review

Intervention not reported

Quality of life measured on multiple scales (0 to 100; higher score = better quality of life) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain
1 finding from 1 review

Intervention not reported

Grief in the relatives ICG (0 to 95; > 25 = presence of complicated grief) measured at 12 months TRIG (21 to 105; lower scores indicate higher levels of grief) measured at 3 and 9 months · relatives, patients, and healthcare professionals during resucitation
1 finding from 1 review

Digital technology (web‐based platform CFHealthHub) vs usual care

Treatment burden · adults (aged 16 years and over) with CF

Digital technology (web‐based platform CFHealthHub) probably leads to higher treatment burden: CFQ‐R treatment burden domain score (higher score… compared with usual care (moderate certainty).

1 finding from 1 review

Intervention not reported

Quality of life (QoL) We reported this outcome narratively in this review. Here, long‐term results (i.e., at the end of treatment) are presented. In the comparison PAZ versus SUN, QoL was measured using FACIT‐F (score range 0‐52; higher scores rep... · people with a confirmed diagnosis of advanced renal cell carcinoma (combined risk groups) without previous systemic anticancer therapy

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Total oocytes ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

MII oocytes ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Duration of stimulation (days) ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Total dose of gonadotropins (IU) ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stumulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Live birth or ongoing pregnancy sensitivity analysis ‐ PCOS (high‐responders) ‐ own oocytes ‐ early phase stimulation protocol ‐ frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in live birth or ongoing pregnancy sensitivity analysis ‐ PCOS… compared with gnRH antagonists; GRADE not reported.

1 finding from 1 review