Findings

What do systematic reviews say?

1,100 questions · 1,164 findings · 107 reviews

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No studies found 280 · 24.1%GRADE not reported 159 · 13.7%Very low 292 · 25.1%Low 274 · 23.5%Moderate 113 · 9.7%High 46 · 4%

Vitamin C vs allopurinol

Withdrawals due to adverse events · participants with chronic gout and sUA level > 0.36mmol/L

1 finding from 1 review

Dietary supplements for chronic gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Intervention not reported

Protein energy wasting (malnutrition) · non‐diabetic adults with CKD

The intervention showed no clear difference in protein energy wasting (malnutrition) (low certainty).

1 finding from 1 review

Low protein diets for non‐diabetic adults with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 1.31 [0.42, 4.13]
15 studies · 2373 participants
Low

Summary of findings: Low sodium intake vs high sodium intake

White population, normotensive, SBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
95 studies · 5982 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Asian population, normotensive, DBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 950 participants
Moderate

Summary of findings: Low sodium intake vs high sodium intake

Asian population, hypertensive, SBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 254 participants
Low

Summary of findings: Low sodium intake vs high sodium intake

Asian population, hypertensive, DBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 254 participants
Low

Summary of findings: Low sodium intake vs high sodium intake

Renin ng/ml/hour · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
91 studies · 2904 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Aldosterone pg/mL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
70 studies · 2506 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Noradrenaline pg/mL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
38 studies · 878 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Adrenaline pg/mL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 331 participants
Moderate

Summary of findings: Low sodium intake vs high sodium intake

Cholesterol mg/dL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
28 studies · 917 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Trigyceride mg/dL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 712 participants
High

Summary of findings: Low sodium intake vs high sodium intake

HDL‐cholesterol · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 738 participants
High

Summary of findings: Low sodium intake vs high sodium intake

White population, normotensive, DBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
96 studies · 6276 participants
High

Summary of findings: Low sodium intake vs high sodium intake

LDL‐cholesterol · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 696 participants
High

Summary of findings: Low sodium intake vs high sodium intake

White population, hypertensive, SBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
88 studies · 3998 participants
High

Summary of findings: Low sodium intake vs high sodium intake

White population, hypertensive, DBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
89 studies · 4032 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Black population, normotensive, SBP mmHg · Black population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 253 participants
Low

Summary of findings: Low sodium intake vs high sodium intake

Black population, normotensive, DBP mmHg · Black population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 253 participants
Low

Summary of findings: Low sodium intake vs high sodium intake

Black population, hypertensive, SBP mmHg · Black population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 398 participants
Low