Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,438 questions · 1,463 findings · 125 reviews · Anaesthesia

No studies found 197 · 13.5%GRADE not reported 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Peripheral nerve block vs systemic analgesia

Pain at rest on arrival in postoperative care unit Visual/verbal analogue scale · adults undergoing elective primary total hip replacement

Peripheral nerve blocks showed no clear difference in pain at rest on arrival in postoperative care unit Visual/verbal… compared with systemic analgesia (moderate certainty).

1 finding from 1 review

Peripheral nerve block vs neuraxial block

Aute confusional state Disorientation · adults undergoing elective primary total hip replacement

It is very uncertain whether peripheral nerve block changes aute confusional state Disorientation compared with neuraxial block (very low certainty).

1 finding from 1 review

Peripheral nerve block vs systemic analgesia

Acute confusional state Complete loss of time and space orientation · adults undergoing elective primary total hip replacement

It is very uncertain whether peripheral nerve blocks changes acute confusional state Complete loss of time and space orientation compared with systemic analgesia (very low certainty).

1 finding from 1 review

Peripheral nerve block vs systemic analgesia

Length of hospital stay · adults undergoing elective primary total hip replacement

It is very uncertain whether peripheral nerve blocks changes hospital length of stay Objective actual measurement compared with systemic analgesia (very low certainty).

1 finding from 1 review

Peripheral nerve block vs systemic analgesia

Walking at postoperative day 1 Objective actual measurement · adults undergoing elective primary total hip replacement

It is very uncertain whether peripheral nerve blocks changes walking at postoperative day 1 Objective actual measurement compared with systemic analgesia (very low certainty).

1 finding from 1 review

Peripheral nerve block vs systemic analgesia

Patient satisfaction Subjective scales · adults undergoing elective primary total hip replacement

Peripheral nerve blocks may leads to higher patient satisfaction Subjective scales compared with systemic analgesia (low certainty).

1 finding from 1 review

Peripheral nerve block vs neuraxial block

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing elective primary total hip replacement

Peripheral nerve block showed no clear difference in pain at rest on arrival in postoperative care unit Verbal/visual… compared with neuraxial block (moderate certainty).

1 finding from 1 review

Intravenous dexamethasone vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · participants undergoing surgery with peripheral nerve block
3 findings from 1 review

Perineural vs intravenous dexamethasone

Incidence of serious adverse events (we used the NIH definition of adverse events. A serious event includes death, a life‐threatening event that requires hospitalization or prolonged hospitalization, disability or congenital anomaly) · peripheral nerve block

The review found no eligible studies for this question.

1 finding from 1 review

Perineural vs intravenous dexamethasone

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · peripheral nerve block
3 findings from 1 review