Cochrane · systematic review · CD011608

Nerve blocks or no nerve blocks for pain control after elective hip replacement (arthroplasty) surgery in adults

Guay, J, Johnson, RL, Kopp, S · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
13
No studies
1
Included studies
NR
No studies 1 · 7.1%Ungraded 0 · 0%Very low 5 · 35.7%Low 4 · 28.6%Moderate 3 · 21.4%High 1 · 7.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Peripheral nerve blocks compared to systemic analgesia for elective primary total hip replacement

Population: adults undergoing elective primary total hip replacement
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain at rest on arrival in postoperative care unit Visual/verbal analogue scale
Peripheral nerve blocks vs systemic analgesia
no estimate extracted9 studies · 429 participantsModerate
Downgraded: risk of bias
Total number of nerve block‐related complications
Peripheral nerve blocks vs systemic analgesia
no estimate extractedNRNo studies
Acute confusional state Complete loss of time and space orientation
Peripheral nerve blocks vs systemic analgesia
RR 0.1 [0.02, 0.54]1 study · 225 participantsVery low
Downgraded: risk of bias, imprecision
Pruritus
Peripheral nerve blocks vs systemic analgesia
RR 0.16 [0.04, 0.7]2 studies · 259 participantsVery low
Downgraded: risk of bias, imprecision
Hospital length of stay Objective actual measurement
Peripheral nerve blocks vs systemic analgesia
SMD 0.752 studies · 249 participantsVery low
Downgraded: risk of bias, imprecision
Walking at postoperative day 1 Objective actual measurement
Peripheral nerve blocks vs systemic analgesia
RD 0.012 studies · 278 participantsVery low
Downgraded: risk of bias, imprecision
Patient satisfaction Subjective scales
Peripheral nerve blocks vs systemic analgesia
SMD 0.67 [0.45, 0.89]5 studies · 363 participantsLow
Downgraded: risk of bias

Peripheral nerve block compared to neuraxial block for elective primary total hip replacement

Population: adults undergoing elective primary total hip replacement
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain at rest on arrival in postoperative care unit Verbal/visual analogue scale. Scale from: 0 to 10
Peripheral nerve block vs neuraxial block
SMD 0.394 studies · 118 participantsModerate
Downgraded: risk of bias
Total number of block‐related complications
Peripheral nerve block vs neuraxial block
RD 05 studies · 334 participantsLow
Downgraded: imprecision
Aute confusional state Disorientation
Peripheral nerve block vs neuraxial block
RR 0.29 [0.01, 6.69]1 study · 50 participantsVery low
Downgraded: risk of bias, imprecision
Pruritus Subjective scale
Peripheral nerve block vs neuraxial block
RR 0.33 [0.19, 0.58]6 studies · 299 participantsModerate
Downgraded: imprecision
Hospital length of stay
Peripheral nerve block vs neuraxial block
MD 0.192 studies · 64 participantsLow
Downgraded: risk of bias, imprecision
Time to first walk
Peripheral nerve block vs neuraxial block
no estimate extracted3 studies · 94 participantsLow
Downgraded: risk of bias, imprecision
Patient satisfaction
Peripheral nerve block vs neuraxial block
SMD 0.086 studies · 307 participantsHigh