Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Oral misoprostol vs vaginal misoprostol

Admission to neonatal intensive care unit · women in the third trimester for induction of labour.

Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal misoprostol (moderate certainty).

1 finding from 1 review

Er,Cr:YSGG laser (erbium,chromium:yttrium-scandium-gallium-garnet) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

Er,Cr:YSGG laser (erbium,chromium:yttrium-scandium-gallium-garnet) showed no clear difference in changes in intensity of pain (VAS 0 to 10) tested through tactile… compared with placebo (placebo laser or placebo agent) or no treatment; GRADE not reported.

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Dental caries: prevalence of moderate to extensive caries (ICDAS 3-6) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with 24-month recall showed no clear difference in dental caries: prevalence of moderate to extensive caries (ICDAS 3-6) compared with clinical examination with 6-month recall (low certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: five to seven months vs three months

Adverse events: hypertension · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: five to… showed no clear difference in adverse events: hypertension compared with three months (moderate certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: hypertension · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: hypertension compared with 2 months of therapy (moderate certainty).

1 finding from 1 review