Colorectal cancer · Adults (general population)
Meta-analysis of observational studies (higher vs lower 1,25(OH)2D) for Colorectal cancer: OR 1.01 (95% CI 0.59 to 1.73), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
OR 1.01 [0.59, 1.73]
4 studies
GRADE not reported
Cardiovascular disease (prevalent) · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Cardiovascular disease (prevalent): OR 0.67 (95% CI 0.55 to 0.82), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
Branemark Mark IV turned titanium implants showed no clear difference in implant failure compared with branemark Mark IV TiUnite oxidised implants; GRADE not reported.
1 finding from 1 review
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
Branemark Mark IV turned titanium implants showed no clear difference in marginal bone level change compared with branemark Mark IV TiUnite oxidised implants; GRADE not reported.
1 finding from 1 review
Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
ITI SLActive titanium grade 4 implants showed no clear difference in implant failure compared with ITI SLActive titanium-13zirconium (Roxolid) implants; GRADE not reported.
1 finding from 1 review
Failure to correct the anterior open bite (open bite not closed) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
Frankel's function regulator-4 (FR-4) with lip-seal training led to lower failure to correct the anterior open bite (open bite not closed) compared with no treatment; GRADE not reported.
1 finding from 1 review
Tuberculosis · Participants in observational studies
The meta-analysis of observational studies reported a SMD (to OR) of 0.29 (95% CI 0.19 to 0.46) for higher versus lower circulating vitamin D concentration.
1 finding from 1 review
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
NobelActive internal connection implants showed no clear difference in marginal bone level change compared with nobelReplace implants; GRADE not reported.
1 finding from 1 review
Birthweight (g) · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Birth weight: WMD 130.9 (95% CI 75.1 to 186.7), statistically significant. Umbrella review outcome-level evidence grade: Probable.
1 finding from 1 review
Ovarian cancer · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Ovarian cancer: OR 0.83 (95% CI 0.63 to 1.09), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
Stroke · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Stroke: RR 0.61 (95% CI 0.50 to 0.75), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Signs and symptoms of respiratory disease · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
The review found no eligible studies for this question.
1 finding from 1 review
Breast cancer · Participants in observational studies
The meta-analysis of observational studies reported a OR of 0.99 (95% CI 0.68 to 1.47) for higher versus lower circulating vitamin D concentration.
1 finding from 1 review
Peri-implantitis · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
Turned (smoother) implant surfaces may leads to lower peri-implantitis compared with roughened implant surfaces (low certainty).
1 finding from 1 review
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
NobelReplace Select Tapered implants showed no clear difference in marginal bone level change compared with nobelReplace Groovy implants; GRADE not reported.
1 finding from 1 review
Colon cancer · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Colon cancer: OR 0.78 (95% CI 0.56 to 1.07), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
Side effects / adverse effects (unilateral crossbite; transverse problems) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
Orthodontic and orthopaedic treatment for anterior open bite in children 2014 · Cochrane All outcomesAbout 4 months (treatment interrupted early)
"After 4 months the open bite was observed to close in the magnet group, but in four out of these ten patients, transverse problems were observed (unilateral crossbite) which led to the interruption of the treatment…
1 study · 10 participants
GRADE not reported
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
NobelActive external connection implants showed no clear difference in marginal bone level change compared with nobelReplace implants; GRADE not reported.
1 finding from 1 review
Position of the incisors (upper incisor inclination) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
The angulation of the upper incisors with the palatal plane (1/ANSPNS) decreased on average 0.3 (SD 4.6) degrees in the control group, whereas in the treated group the mean retrusion was 4 (SD 4.6) degrees, P < 0.01.…
1 study
GRADE not reported