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Evidence found and GRADE certainty

1,057 questions · 1,077 findings · 32 reviews · Skin

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No studies found 395 · 36.7%GRADE not reported 89 · 8.3%Very low 172 · 16%Low 177 · 16.4%Moderate 191 · 17.7%High 53 · 4.9%

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyloestradiol and norgestrel

Number of participants reporting non‐serious adverse effects · participants with hidradenitis suppurativa

Ethinyloestradiol and cyproterone acetate probably leads to lower number of participants reporting non‐serious adverse effects compared with ethinyloestradiol and norgestrel (moderate certainty).

1 finding from 1 review

Gentamicin sponge vs primary closure

Adverse effects ‐ complication rate at 1 week after surgery · participants with hidradenitis suppurativa

Gentamicin sponge showed no clear difference in adverse effects ‐ complication rate at 1 week after surgery compared with primary closure alone (moderate certainty).

1 finding from 1 review

Gentamicin sponge vs primary closure

Adverse effects ‐ complication rate at 3 months after surgery · participants with hidradenitis suppurativa

Gentamicin sponge showed no clear difference in adverse effects ‐ complication rate at 3 months after surgery compared with primary closure alone (moderate certainty).

1 finding from 1 review

Gentamicin sponge vs primary closure

Recurrence after surgery · participants with hidradenitis suppurativa

Gentamicin sponge showed no clear difference in recurrence rate at 3 months after surgery compared with primary closure alone (moderate certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light may leads to higher participant global assessment: satisfaction with treatment… compared with no treatment (low certainty).

1 finding from 1 review

Adalimumab weekly vs placebo

Frequency of serious adverse effects · participants with hidradenitis suppurativa

Adalimumab weekly showed no clear difference in frequency of serious adverse effects compared with placebo (moderate certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment ‐ axilla Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light may leads to higher participant global assessment: satisfaction with treatment ‐ axilla… compared with no treatment (low certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment ‐ groin Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light showed no clear difference in participant global assessment: satisfaction with treatment ‐ groin… compared with no treatment (low certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment ‐ inframammary Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light showed no clear difference in participant global assessment: satisfaction with treatment ‐… compared with no treatment (low certainty).

1 finding from 1 review

Adalimumab weekly vs placebo

Treatment discontinuation · participants with hidradenitis suppurativa

Adalimumab weekly showed no clear difference in frequency of treatment discontinuation compared with placebo (moderate certainty).

1 finding from 1 review