Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Apatinib plus chemotherapy or chemotherapy/brachytherapy vs chemotherapy or chemotherapy/brachytherapy

Adverse events: hypertension · women with recurrent or FIGO stage IVB cervical cancer

Apatinib plus chemotherapy or chemotherapy/brachytherapy may leads to higher specific adverse events: hypertension compared with chemotherapy or chemotherapy/brachytherapy (low certainty).

1 finding from 1 review

Bevacizumab plus chemotherapy vs chemotherapy alone

Adverse events: hypertension · women with persistent, recurrent, or metastatic cervical cancer

Bevacizumab plus chemotherapy probably leads to higher specific adverse events: hypertension compared with chemotherapy (moderate certainty).

1 finding from 1 review

100 mg olorinab 3 times/day vs 25 mg olorinab 3 times/day

At least 30% reduction in pain · people with Crohn's disease

It is very uncertain whether 100 mg olorinab 3 times/day changes pain intensity (30% reduction in weekly AAPS) compared with 25 mg olorinab 3 times/day (very low certainty).

1 finding from 1 review

Kefir ( Lactobacillus bacteria) vs no intervention

Pain intensity (measure on a 0‐3 four‐point scale) · people with inflammatory bowel disease
2 findings from 1 review