Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

FLUPHENAZINE (ORAL) vs OLANZAPINE

Clinically important response (defined by study) ‐ short term (up to 12 weeks) decreased rate of PANSS score < 40%, decreased rate of BPRS score < 40% · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes clinically important response (defined by study) ‐ short term (up to… compared with OLANZAPINE (very low certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs AMISULPRIDE

Adverse effects: Extrapyramidal effects ‐ concomitant anticholinergic medication ‐ short term (up to 12 weeks) Participants requiring concomitant anticholinergic medication · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes adverse effects: Extrapyramidal effects ‐ concomitant… compared with AMISULPRIDE (very low certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs RISPERIDONE

Clinically important response (defined by study) ‐ short term (up to 12 weeks) decreased rate of BPRS score < 20% · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes clinically important response (defined by study) ‐ short term (up to… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

PVP‐hydrogel‐filled vs saline‐filled implants

Short‐term complications Number of women with at least one short‐term complication · women having reconstructive breast surgery

It is very uncertain whether PVP‐hydrogel‐filled changes short‐term complications Number of women with at least one… compared with saline‐filled implants (very low certainty).

1 finding from 1 review

Anatomical vs round implants

Short‐term complications Number of women with at least one short‐term complication · women having reconstructive breast surgery

It is very uncertain whether anatomical changes short‐term complications Number of women with at least one… compared with round implants (very low certainty).

1 finding from 1 review