Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,103 questions · 1,157 findings · 177 reviews · Headline outcomes only

No studies found 291 · 25.2%GRADE not reported 85 · 7.3%Very low 317 · 27.4%Low 258 · 22.3%Moderate 169 · 14.6%High 37 · 3.2%

Chloral hydrate oral (50 mg/kg) vs sodium thiopental rectal (25 mg/kg)

Number of children with clinical adverse event: diarrhoea · children undergoing neurodiagnostic procedures

Chloral hydrate oral (50 mg/kg) probably leads to lower number of children with clinical adverse event: diarrhoea compared with sodium thiopental rectal (25 mg/kg) (moderate certainty).

1 finding from 1 review

Traditional suburethral sling operation vs open abdominal retropubic suspension

Number of continent (dry) women (any definition) in the medium term (1 to 5 years) · women with urinary incontinence

Traditional suburethral sling operation probably leads to higher number of continent (dry) women (any definition) in the medium term… compared with open abdominal retropubic colposuspension (moderate certainty).

1 finding from 1 review

Traditional suburethral sling operation vs open abdominal retropubic suspension

Repeat surgery for urinary incontinence‐stress urinary incontinence (symptoms only) · women with urinary incontinence

Traditional suburethral sling operation leads to lower repeat surgery for urinary incontinence‐stress urinary incontinence… compared with open abdominal retropubic colposuspension (high certainty).

1 finding from 1 review

Traditional suburethral sling operation vs open abdominal retropubic suspension

Perioperative surgical complications · women with urinary incontinence

It is very uncertain whether traditional suburethral sling operation changes perioperative surgical complications compared with open abdominal retropubic colposuspension (very low certainty).

1 finding from 1 review

Traditional suburethral sling operation vs open abdominal retropubic suspension

Long‐term adverse effects Number of women with recurrent UTIs at > 5 years · women with urinary incontinence

Traditional suburethral sling operation showed no clear difference in long‐term adverse effects Number of women with recurrent UTIs at > 5… compared with open abdominal retropubic colposuspension (low certainty).

1 finding from 1 review

Laparoscopic colposuspension vs open colposuspension

Subjective cure within 18 months: laparoscopic colposuspension using sutures · women with urinary incontinence

Laparoscopic colposuspension showed no clear difference in subjective cure within 18 months: laparoscopic colposuspension using… compared with open colposuspension (high certainty).

1 finding from 1 review

Laparoscopic colposuspension vs open colposuspension

Subjective cure within 18 months: laparoscopic colposuspension using mesh and staples · women with urinary incontinence

It is very uncertain whether laparoscopic colposuspension changes subjective cure within 18 months: laparoscopic colposuspension using… compared with open colposuspension (very low certainty).

1 finding from 1 review