Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,413 questions · 2,602 findings · 93 reviews · All outcomes

No studies found 452 · 17.4%GRADE not reported 1,582 · 60.8%Very low 392 · 15.1%Low 122 · 4.7%Moderate 53 · 2%High 1 · 0%

Ball (stud) attachment system vs Bar attachment system

Prosthodontic maintenance (general categorization) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
1 finding from 1 review

Pedicled buccal fat pad flap (PBFPF) vs Buccal flap (BF)

Successful (complete) closure of oro-antral communication · People of any age with oro-antral communications, fistulae, or both caused by dental procedures

It is very uncertain whether pedicled buccal fat pad flap (PBFPF) changes successful (complete) closure of oro-antral communication compared with buccal flap (BF) (very low certainty).

1 finding from 1 review

Ball (stud) attachment system vs Telescopic attachment system

Patient satisfaction / quality of life (validated measure) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Adverse events · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Ball (stud) attachment system vs Magnetic attachment system

Patient satisfaction / quality of life (validated measure) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
1 finding from 1 review

Ball (stud) attachment system vs Magnetic attachment system

Prosthodontic maintenance (general categorization) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
1 finding from 1 review

Ball (stud) attachment system vs Magnetic attachment system

Re-treatment: repair of attachment system (medium term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)

It is very uncertain whether ball (stud) attachment system changes re-treatment: repair of attachment system (medium term) compared with magnetic attachment system (very low certainty).

1 finding from 1 review

Ball (stud) attachment system vs Telescopic attachment system

Prosthodontic maintenance: reline of implant overdenture (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)

It is very uncertain whether ball (stud) attachment system changes prosthodontic maintenance: reline of implant overdenture (short term) compared with telescopic attachment system (very low certainty).

1 finding from 1 review

Ball (stud) attachment system vs Telescopic attachment system

Prosthodontic maintenance: matrix replaced (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)

It is very uncertain whether ball (stud) attachment system changes prosthodontic maintenance: matrix replaced (short term) compared with telescopic attachment system (very low certainty).

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Costs: direct cost of treatment · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Keratinocyte growth factor (KGF; palifermin or repifermin), intravenous vs placebo

Normalcy of diet (mean worst ability to eat, 1 to 4 scale) · Adults with cancer receiving treatment

Keratinocyte growth factor (KGF; palifermin or repifermin),… showed no clear difference in normalcy of diet (mean worst ability to eat, 1 to 4 scale) compared with placebo; GRADE not reported.

1 finding from 1 review

Ibuprofen taken pre-emptively (about 1 hour before treatment) vs Ibuprofen taken post-treatment

Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

Ibuprofen taken pre-emptively (about 1 hour before treatment) showed no clear difference in rescue analgesia compared with ibuprofen taken post-treatment; GRADE not reported.

1 finding from 1 review

Intestinal trefoil factor (ITF), oral spray vs placebo

Oral mucositis (moderate to severe) · Adults receiving chemotherapy alone for colorectal cancer

Intestinal trefoil factor (ITF), oral spray led to lower oral mucositis (moderate to severe) compared with placebo; GRADE not reported.

1 finding from 1 review

Bethanechol vs Artificial saliva

Dry mouth (xerostomia) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

Bethanechol showed no clear difference in xerostomia (dry mouth, yes/no) compared with artificial saliva; GRADE not reported.

2 findings from 1 review

G‐CSF vs placebo or no treatment

Interruptions to cancer treatment (radiotherapy interruptions) · Adults with cancer receiving treatment

Granulocyte-colony stimulating factor (G-CSF) showed no clear difference in interruptions to cancer treatment (radiotherapy interruptions) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash vs Sucralfate mouthwash

Interruptions to cancer treatment · Adults receiving radiotherapy to the head and neck

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash showed no clear difference in interruptions to cancer treatment compared with sucralfate mouthwash; GRADE not reported.

1 finding from 1 review