Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

954 questions · 963 findings · 130 reviews · Headline outcomes only

No studies found 181 · 18.8%GRADE not reported 71 · 7.4%Very low 163 · 16.9%Low 311 · 32.3%Moderate 163 · 16.9%High 74 · 7.7%

Admission cardiotocography vs intermittent auscultation

Instrumental vaginal birth · Low risk pregnant women. All of the women were in labour.

Admission cardiotocography showed no clear difference in incidence of operative vaginal birth compared with intermittent auscultation (low‐risk women) (low certainty).

1 finding from 1 review

Admission cardiotocography vs intermittent auscultation

Incidence and severity of hypoxic ischaemic encephalopathy (incidence only reported) · Low risk pregnant women. All of the women were in labour.

It is very uncertain whether admission cardiotocography changes incidence and severity of hypoxic ischaemic encephalopathy… compared with intermittent auscultation (low‐risk women) (very low certainty).

1 finding from 1 review

Admission cardiotocography vs intermittent auscultation

Neonatal seizures · Low risk pregnant women. All of the women were in labour.

Admission cardiotocography showed no clear difference in incidence of seizures in the neonatal period compared with intermittent auscultation (low‐risk women) (low certainty).

1 finding from 1 review

PCT vs non‐PCT (standard care or CRP: primary outcomes)

Mortality at 28 days · adult patients with sepsis, severe sepsis and septic shock

PCT showed no clear difference in mortality at 28 days compared with non‐PCT (standard care or CRP: primary outcomes) (low certainty).

1 finding from 1 review

PCT vs non‐PCT (standard care or CRP: primary outcomes)

Mortality at ICU discharge · adult patients with sepsis, severe sepsis and septic shock

PCT showed no clear difference in mortality at ICU discharge compared with non‐PCT (standard care or CRP: primary outcomes) (low certainty).

1 finding from 1 review

PCT vs non‐PCT (standard care or CRP: primary outcomes)

Death at hospital discharge · adult patients with sepsis, severe sepsis and septic shock

PCT showed no clear difference in mortality at hospital discharge compared with non‐PCT (standard care or CRP: primary outcomes) (moderate certainty).

1 finding from 1 review