PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – OS‐LE vs S‐LE · Parenterally fed preterm infants
Alternative lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – OS‐LE vs S‐LE compared with soybean oil‐based LE (S‐LE) (low certainty).
1 finding from 1 review
PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – all fish oil LE vs non‐fish oil LE (combined subgroups) · Parenterally fed preterm infants
Fish oil lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – all fish oil LE… compared with non‐fish oil LE (low certainty).
1 finding from 1 review
Death at hospital discharge · Parenterally fed preterm infants
Alternative lipid emulsion (LE) showed no clear difference in death before discharge – OS‐LE vs S‐LE compared with soybean oil‐based LE (S‐LE) (low certainty).
1 finding from 1 review
Death of baby (up to discharge) · Parenterally fed preterm infants
1 finding from 1 review
Any ROP – OS‐LE vs S‐LE · Parenterally fed preterm infants
It is very uncertain whether alternative lipid emulsion (LE) changes any ROP – OS‐LE vs S‐LE compared with soybean oil‐based LE (S‐LE) (very low certainty).
1 finding from 1 review
Culture‐positive sepsis · Parenterally fed preterm infants
Alternative lipid emulsion (LE) showed no clear difference in culture‐positive sepsis – OS‐LE vs S‐LE compared with soybean oil‐based LE (S‐LE) (low certainty).
1 finding from 1 review
Conjugated bilirubin levels · Parenterally fed preterm infants
1 finding from 1 review
Growth · Parenterally fed preterm infants
1 finding from 1 review
PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – MS‐LE vs OS‐LE · Parenterally fed preterm infants
Alternative lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – MS‐LE vs OS‐LE compared with another alternative‐LE (low certainty).
1 finding from 1 review
Death at hospital discharge · Parenterally fed preterm infants
1 finding from 1 review
Oxygen requirement at 36 weeks' postmenstrual age · Parenterally fed preterm infants
Alternative lipid emulsion (LE) showed no clear difference in CLD (oxygen requirement at 36 weeks' postmenstrual age) – MS‐LE vs… compared with another alternative‐LE (low certainty).
1 finding from 1 review
PNALD/cholestasis (any definition: low and unclear risk of bias studies) – all fish oil LE vs non‐fish oil LE · Parenterally fed preterm infants
Fish oil lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (any definition: low and unclear risk of bias… compared with non‐fish oil LE (low certainty).
1 finding from 1 review
Any sepsis (clinical and/or culture positive) · Parenterally fed preterm infants
Alternative lipid emulsion (LE) showed no clear difference in any sepsis (clinical or culture positive (or both)) – MS‐LE vs OS‐LE compared with another alternative‐LE (low certainty).
1 finding from 1 review
Conjugated bilirubin levels · Parenterally fed preterm infants
1 finding from 1 review
PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – pure F‐LE vs S‐LE · parenterally fed preterm infants with surgical conditions
It is very uncertain whether fish oil lipid emulsion (LE) changes PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – pure F‐LE vs S‐LE compared with non‐fish oil LE (very low certainty).
1 finding from 1 review
Death at hospital discharge · parenterally fed preterm infants with surgical conditions
1 finding from 1 review
Culture‐positive sepsis · parenterally fed preterm infants with surgical conditions
It is very uncertain whether fish oil lipid emulsion (LE) changes culture‐positive sepsis – pure F‐LE vs S‐LE compared with non‐fish oil LE (very low certainty).
1 finding from 1 review
Conjugated bilirubin levels · parenterally fed preterm infants with surgical conditions
1 finding from 1 review
Neurodevelopmental outcomes · parenterally fed preterm infants with surgical conditions
2 findings from 1 review
Resolution of PNALD/ cholestasis (conjugated bilirubin < 2 mg/dL) Pure F‐LE vs Intralipid · parenterally fed preterm infants with cholestasis
It is very uncertain whether fish oil lipid emulsion (LE) changes resolution of PNALD/ cholestasis (conjugated bilirubin < 2 mg/dL)… compared with non‐fish oil LE (very low certainty).
1 finding from 1 review