Findings

What do systematic reviews say?

864 questions · 895 findings · 140 reviews · Headline outcomes only

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No studies found 202 · 22.6%GRADE not reported 53 · 5.9%Very low 227 · 25.4%Low 254 · 28.4%Moderate 131 · 14.6%High 28 · 3.1%

CSII vs MDI: infant outcomes

Adiposity (infant) · infants of pregnant women with diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CSII vs MDI: infant outcomes

Neurosensory disability · infants of pregnant women with diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CSII vs MDI: maternal outcomes

Caesarean section · pregnant women with diabetes

It is very uncertain whether CSII changes caesarean section compared with MDI: maternal outcomes (very low certainty).

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
RR 1.09 [0.66, 1.77]
3 studies · 71 participants
Very low

CSII vs MDI: maternal outcomes

Development of type 2 diabetes · pregnant women with diabetes

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CSII vs MDI: maternal outcomes

Perineal trauma · pregnant women with diabetes

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CSII vs MDI: maternal outcomes

Return to pre‐pregnancy weight · pregnant women with diabetes

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CSII vs MDI: maternal outcomes

Postnatal depression · pregnant women with diabetes

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CSII vs MDI: maternal outcomes

Induction of labour · pregnant women with diabetes

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CSII vs MDI: infant outcomes

Large‐for‐gestational age · infants of pregnant women with diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CSII vs MDI: infant outcomes

Neonatal hypoglycaemia · infants of pregnant women with diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Mortality · patients with acute kidney injury

The intervention showed no clear difference in mortality (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.76 [0.5, 1.15]
3 studies · 163 participants
Moderate

Intervention not reported

Serum bicarbonate (mmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 163 participants
Low

Intervention not reported

Serum creatinine (µmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 137 participants
Low

Intervention not reported

Serum lactate (mmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 171 participants
Moderate

Intervention not reported

Serum base excess · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 145 participants
Low

Intervention not reported

Serum pH · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 171 participants
Low

Intervention not reported

pCO2 · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 151 participants
Low

Intervention not reported

Hypotensive events · patients with acute kidney injury

The intervention probably leads to lower hypotensive events (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.44 [0.26, 0.75]
1 study · 20 participants
Moderate

Intervention not reported

Cardiovascular complications · patients with acute kidney injury

The intervention probably leads to lower cardiovascular complications (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.39
1 study · 20 participants
Moderate

Intervention not reported

All‐cause mortality · patients with rhabdomyolysis

The intervention showed no clear difference in all‐cause mortality (low certainty).

1 finding from 1 review

Continuous renal replacement therapy (CRRT) for rhabdomyolysis 2014 · Cochrane Headline outcomes only
RR 0.17 [0.02, 1.37]
1 study · 43 participants
Low