Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

948 questions · 998 findings · 100 reviews · Headline outcomes only

No studies found 233 · 23.3%GRADE not reported 40 · 4%Very low 203 · 20.3%Low 271 · 27.2%Moderate 176 · 17.6%High 75 · 7.5%

Steroids vs vitamin D

Number of participants withdrawing due to adverse events (AE) · scalp psoriasis

Steroid probably leads to lower number of participants withdrawing due to adverse events (AE) compared with vitamin D (moderate certainty).

1 finding from 1 review

Steroids vs vitamin D

Number of participants achieving 'response' by PGA · scalp psoriasis

Steroid probably leads to higher number of participants achieving 'response' by PGA compared with vitamin D (moderate certainty).

1 finding from 1 review

Quinine vs vitamin E

Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review

High‐dose vs low‐dose coenzyme Q10 and vitamin E

Short‐term (within 1 month) change in isolated movement, objective and subjective measures of speech production Cooper 2008 reported 3 speech measures: ICARS speech subscale. Scale from: 0 to 8. Higher scores indicate greater clinical severity Syl... · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review

Lutein with or without zeaxanthin vs placebo

Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with AMD

Lutein with or without zeaxanthin showed no clear difference in progression to visual loss (loss of 3 or more lines on logMAR chart) compared with placebo (low certainty).

1 finding from 1 review