Serious adverse events · people with surgically‐induced remission in Crohn's disease
It is very uncertain whether azathioprine or 6‐mercaptopurine changes serious adverse events compared with anti TNF‐α (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with surgically‐induced remission in Crohn's disease
Azathioprine or 6‐mercaptopurine showed no clear difference in withdrawal due to adverse events compared with anti TNF‐α (low certainty).
1 finding from 1 review
Radiologic relapse · people with surgically‐induced remission in Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · people with surgically‐induced remission in Crohn's disease
Azathioprine or 6‐mercaptopurine showed no clear difference in adverse events compared with placebo (low certainty).
1 finding from 1 review
Serious adverse events · people with surgically‐induced remission in Crohn's disease
Azathioprine or 6‐mercaptopurine showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with surgically‐induced remission in Crohn's disease
Azathioprine or 6‐mercaptopurine showed no clear difference in withdrawal due to adverse events compared with placebo (moderate certainty).
1 finding from 1 review
Clinical relapse · people with surgically‐induced remission in Crohn's disease
Azathioprine or 6‐mercaptopurine showed no clear difference in clinical relapse compared with 5‐aminosalicylic acid (low certainty).
1 finding from 1 review
Endoscopic relapse · people with surgically‐induced remission in Crohn's disease
It is very uncertain whether azathioprine or 6‐mercaptopurine changes endoscopic relapse compared with 5‐aminosalicylic acid (very low certainty).
1 finding from 1 review
Intervention not reported
Placebo Comparator · surgically induced remission in Crohn's disease
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Intervention not reported
Sulfasalazine (2 RCTs; 143 participants) · surgically induced remission in Crohn's disease
It is very uncertain whether the intervention changes sulfasalazine (2 RCTs; 143 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Antibiotics (2 RCTs; 57 participants) · surgically induced remission in Crohn's disease
It is very uncertain whether the intervention changes antibiotics (2 RCTs; 57 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Probiotics (2 RCTs; 105 participants) · surgically induced remission in Crohn's disease
It is very uncertain whether the intervention changes probiotics (2 RCTs; 105 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Sulfasalazine + prednisolone (1 RCT; 57 participants) · surgically induced remission in Crohn's disease
It is very uncertain whether the intervention changes sulfasalazine + prednisolone (1 RCT; 57 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Placebo (16 RCTs; 935 participants) · surgically induced remission in Crohn's disease
1 finding from 1 review
Intervention not reported
Adalimumab (3 RCTs; 37 participants) · surgically induced remission in Crohn's disease
The intervention may leads to lower adalimumab (3 RCTs; 37 participants) (low certainty).
1 finding from 1 review
Intervention not reported
Infliximab (2 RCTs; 21 participants) · surgically induced remission in Crohn's disease
The intervention showed no clear difference in infliximab (2 RCTs; 21 participants) (low certainty).
1 finding from 1 review
Intervention not reported
Antibiotics (2 RCTs; 57 participants) · surgically induced remission in Crohn's disease
It is very uncertain whether the intervention changes antibiotics (2 RCTs; 57 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Purine analogues (4 RCTs; 164 participants) · surgically induced remission in Crohn's disease
It is very uncertain whether the intervention changes purine analogues (4 RCTs; 164 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Probiotics (3 RCTs; 108 participants) · surgically induced remission in Crohn's disease
It is very uncertain whether the intervention changes probiotics (3 RCTs; 108 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Rank 8 (6 to 10) · surgically induced remission in Crohn's disease
1 finding from 1 review
no estimate extracted
Studies not reported
Low