Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Shunting vs no shunting

Stroke‐related death within 30 days of surgery (worst‐case) · patients with symptomatic or asymptomatic carotid disease

Shunting showed no clear difference in stroke‐related death within 30 days of surgery (worst‐case) compared with no shunting (low certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs H2RA, placebo or no treatment

Surgery ‐ within 30 days · people with upper gastrointestinal bleeding prior to endoscopic diagnosis

Proton pump inhibitor treatment showed no clear difference in surgery ‐ within 30 days compared with H2RA, placebo or no treatment (low certainty).

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term emergency surgery during · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term emergency surgery within 30 days · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term emergency surgery during · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term emergency surgery within 30 days · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in primary ‐ Short‐term emergency surgery within 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term emergency surgery during · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in secondary ‐ Long‐term emergency surgery during (low certainty).

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term emergency surgery within 30 days · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in primary ‐ Short‐term emergency surgery within 30 days (low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects: CO2 laser plus TAC versus cryosurgery plus TAC ‐ atrophy ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects: CO2 laser plus TAC… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ CO2 laser plus TAC versus cryosurgery plus TAC ‐ erythema ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ CO2 laser plus TAC… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ CO2 laser plus TAC versus cryosurgery plus TAC ‐ telangiectasia ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ CO2 laser plus TAC… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ CO2 laser plus TAC versus cryosurgery plus TAC ‐ hypopigmentation ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ CO2 laser plus TAC… compared with other treatment (very low certainty).

1 finding from 1 review