Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

807 questions · 849 findings · 68 reviews · Headline outcomes only

No studies found 236 · 27.8%GRADE not reported 50 · 5.9%Very low 266 · 31.3%Low 168 · 19.8%Moderate 104 · 12.2%High 25 · 2.9%

Gabapentin vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with pain in Guillain‐Barré syndrome

It is very uncertain whether gabapentin changes pain score (numerical rating scale of 0 to 10: 0 = no pain, 10 =… compared with placebo (very low certainty).

1 finding from 1 review

Gabapentin vs placebo

Sedation score (numerical rating scale of 1 to 6: 0 = anxious, agitated, or restless, 6 = asleep, no response) · patients with pain in Guillain‐Barré syndrome

It is very uncertain whether gabapentin changes sedation score (numerical rating scale of 1 to 6: 0 = anxious,… compared with placebo (very low certainty).

1 finding from 1 review