Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

966 questions · 1,015 findings · 90 reviews · Headline outcomes only

No studies found 256 · 25.2%GRADE not reported 62 · 6.1%Very low 271 · 26.7%Low 269 · 26.5%Moderate 111 · 10.9%High 46 · 4.5%

PUFA vs monounsaturated fatty acid (MUFA)

Global impression of deterioration (investigator defined global impression of deterioration) · people with multiple sclerosis

Polyunsaturated fatty acid (PUFA) showed no clear difference in global impression of deterioration (investigator defined global… compared with monounsaturated fatty acid (MUFA) (low certainty).

1 finding from 1 review

Omega‐3 vs omega‐6

Global impression of deterioration (investigator defined global impression of deterioration) · people with multiple sclerosis

Omega‐3 showed no clear difference in global impression of deterioration (investigator defined global… compared with omega‐6 (moderate certainty).

1 finding from 1 review

Physical activity interventions with a caregiver component vs interventions without a caregiver component

Children's percentage of total energy intake from saturated fat Measured by food frequency questionnaire and 24‐hour recall · children aged 3 to 11 years

The review found no eligible studies for this question.

1 finding from 1 review