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Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

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No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Topical corticosteroids vs Another topical agent or placebo

Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
    No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo

Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
    No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Topical corticosteroids vs Another topical agent or placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
    No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo

Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
    No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Topical corticosteroids vs Another topical agent or placebo

Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
    No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Intervention not reported

Death within 5 years · patients with early‐stage cervical cancer (FIGO stages IB1, IB2 or IIA)

The intervention showed no clear difference in death within 5 years (moderate certainty).

1 finding from 1 review

Intervention not reported

Disease progression within 5 years · patients with early‐stage cervical cancer (FIGO stages IB1, IB2 or IIA)

The intervention probably leads to lower disease progression within 5 years (moderate certainty).

1 finding from 1 review

Topical thalidomide vs Another topical agent or placebo

Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
    No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Topical thalidomide vs Another topical agent or placebo

Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
    No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Open reduction and fixation vs Closed (conservative) management (no active intervention other than soft diet, analgesics or antibiotics; or intermaxillary/maxillary-mandibular fixation with rigid or elastic traction)

Outcome not reported · Adults, over 18 years of age, with unilateral or bilateral fractures of the mandibular condyles

The review found no eligible studies for this question.

1 finding from 1 review