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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Pressure‐garment therapy (PGT) vs silicone
Pain (POSAS 0–10, higher score = more severe pain, VAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted2 studies · 263 participantsVery low
Pressure‐garment therapy (PGT) vs silicone
Pruritus (POSAS 0–10, higher score = more severe pruritus; TPIS 0–3, higher score = more severe pruritus; VAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted2 studies · 263 participantsVery low
Pressure‐garment therapy (PGT) vs silicone
Quality of life (CHU‐9D 0–1, with 1 representing full health; BBSIP 0–5, higher scores = more severe impact) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Pressure‐garment therapy (PGT) vs silicone
Adverse events · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Pressure‐garment therapy (PGT) vs silicone
Adherence · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs no treatment/lanolin
Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 96 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs no treatment/lanolin
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Pressure‐garment therapy (PGT) plus silicone vs no treatment/lanolin
Pain (VAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 104 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs no treatment/lanolin
Pruritus (VAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 104 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs no treatment/lanolin
Quality of life · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Pressure‐garment therapy (PGT) vs no treatment/lanolin
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Pressure‐garment therapy (PGT) plus silicone vs no treatment/lanolin
Adverse events · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 104 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs no treatment/lanolin
Adherence · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Pressure‐garment therapy (PGT) plus silicone vs silicone
Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 96 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs silicone
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs silicone
Pain (POSAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs silicone
Pruritus (POSAS 0–10, higher score = more severe pruritus; TPIS 0–3, higher score = more severe pruritus; VAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted2 studies · 263 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs silicone
Quality of life (CHU‐9D 0–1, with 1 representing full health; BBSIP 0–5, higher scores = more severe impact) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs silicone
Adverse events · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Pressure‐garment therapy (PGT) plus silicone vs silicone
Adherence · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone
Scar improvement (VSS) (0–14, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 88 participantsVery low
Pressure‐garment therapy (PGT) vs no treatment/lanolin
Pain (VAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 104 participantsVery low
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 88 participantsVery low
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone
Pain (POSAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 88 participantsVery low
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone
Pruritus (POSAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 88 participantsVery low
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone
Quality of life (EQ‐5D‐5L 0–1, with 1 representing full health) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 88 participantsVery low
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone
Adverse events · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 88 participantsVery low
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone
Adherence · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 88 participantsVery low
High‐pressure garment therapy vs low‐pressure garment therapy
Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 58 participantsVery low
High‐pressure garment therapy vs low‐pressure garment therapy
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
High‐pressure garment therapy vs low‐pressure garment therapy
Pain · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
High‐pressure garment therapy vs low‐pressure garment therapy
Pruritus · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Pressure‐garment therapy (PGT) vs no treatment/lanolin
Pruritus (VAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 104 participantsVery low
High‐pressure garment therapy vs low‐pressure garment therapy
Quality of life · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
High‐pressure garment therapy vs low‐pressure garment therapy
Adverse events · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 60 participantsVery low
High‐pressure garment therapy vs low‐pressure garment therapy
Adherence · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 67 participantsVery low
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage))
Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage))
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage))
Pain (POSAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage))
Pruritus (POSAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage))
Quality of life · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage))
Adverse events · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage))
Adherence · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Pressure‐garment therapy (PGT) vs no treatment/lanolin
Quality of life · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Pressure‐garment therapy (PGT) vs no treatment/lanolin
Adverse events · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 1 participantsUngraded
Pressure‐garment therapy (PGT) vs no treatment/lanolin
Adherence · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extractedNRNo studies
Pressure‐garment therapy (PGT) vs silicone
Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 96 participantsVery low
Pressure‐garment therapy (PGT) vs silicone
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane
no estimate extracted1 study · 159 participantsVery low
Summary of findings table ‐ Off‐midline closure vs conventional midline closure
Time to wound healing · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extracted3 studies · 300 participantsModerate
Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure
Recurrence rate · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 0.69 [0.3, 1.61]6 studies · 551 participantsVery low