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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,589 questions in 168 reviews · Schizophrenia

current versions
No studies 601 · 23.2%Ungraded 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Global state: Average endpoint score CGAS (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 50 participantsVery low
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Cognitive functioning: Attaining normal cognitive functioning ‐ Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Global functioning: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Adverse events: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Service Use: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Leaving the study early: For any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
RR 0.43 [0.15, 1.28]1 study · 56 participantsVery low
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Global State: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Mental State: Mean endpoint total score on PANSS (high score = poor) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 48 participantsVery low
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Cognitive functioning: Attaining normal cognitive functioning ‐ Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Global functioning: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Adverse events: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Mental state: Average endpoint score PANNS (high score = poor) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 50 participantsVery low
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Service Utilisation: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Leaving the study early: For any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
RR 0.71 [0.25, 2]1 study · 60 participantsLow
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Global state: Average endpoint score GAS (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 25 participantsVery low
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Mental state: Average endpoint score BPRS (high score = poor) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 25 participantsVery low
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Cognitive functioning: Mean endpoint score SPAN‐12 (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 25 participantsVery low
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Global functioning: Clinically important change ‐ as defined by each of the studies · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Adverse effects: Clinically important adverse effect ‐ as defined by each of the studies · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Service use: Hospital admission for any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Leaving the study early: For any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Global state: Average endpoint score HoNOSCA (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 32 participantsVery low
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Cognitive functioning: clinically important change Not attaining normal cognitive function (Memory Digit Span) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
RR 0.58 [0.37, 0.89]1 study · 31 participantsVery low
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Mental state: Average endpoint score PANNS (high score = poor) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 32 participantsVery low
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Cognitive functioning: Average endpoint score RBANS (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 32 participantsVery low
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Global functioning: Average endpoint score SOFAS (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 32 participantsVery low
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Adverse events: Clinically important change · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Service use: Hospital admission · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Leaving the study early: For any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
RR 2.33 [0.27, 20.09]1 study · 32 participantsVery low
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Global state: Mean endpoint score CGAS (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 49 participantsVery low
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Mental State: Mean end point score PANSS ‐ (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 49 participantsVery low
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Cognitive functioning: Attaining normal cognitive functioning ‐ Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Global functioning: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Global functioning: Average endpoint VABS Score (high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 50 participantsVery low
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Adverse events: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Service use: Number of participants needing admission · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
RR 0.84 [0.36, 1.96]1 study · 49 participantsLow
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Leaving the study early: For any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
RR 0.52 [0.1, 2.6]1 study · 55 participantsLow
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Adverse events: Clinically important effect · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Service use: Hospital admission for any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Leaving the study early: For any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
RR 0.93 [0.32, 2.71]2 studies · 91 participantsVery low
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Global state: Mean endpoint score (CGAS, high score = good) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 56 participantsVery low
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Mental State: Mean endpoint total score on PANSS (high score = poor) · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extracted1 study · 56 participantsVery low
Avatar Therapy vs treatment
Mental state*: specific – positive – average endpoint score (PANSS‐P, high = poor) – short term · schizophrenia or related disorders
Avatar Therapy for people with schizophrenia or related disorders (2020) · Cochrane
no estimate extracted1 study · 19 participantsVery low
Avatar Therapy vs supportive counselling (all short‐term)
Global state: relapse (rehospitalised) · schizophrenia or related disorders
Avatar Therapy for people with schizophrenia or related disorders (2020) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Avatar Therapy vs supportive counselling (all short‐term)
Leaving study early: for any reason – short term · schizophrenia or related disorders
Avatar Therapy for people with schizophrenia or related disorders (2020) · Cochrane
RR 1.061 study · 150 participantsModerate
Avatar Therapy vs supportive counselling (all short‐term)
Adverse events – anxiety – after first session · schizophrenia or related disorders
Avatar Therapy for people with schizophrenia or related disorders (2020) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Avatar Therapy vs supportive counselling (all short‐term)
Quality of life: average endpoint score (MANSA, high = good) – short term · schizophrenia or related disorders
Avatar Therapy for people with schizophrenia or related disorders (2020) · Cochrane
no estimate extracted1 study · 120 participantsLow
Avatar Therapy vs supportive counselling (all short‐term)
Functioning: clinically important change · schizophrenia or related disorders
Avatar Therapy for people with schizophrenia or related disorders (2020) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Avatar Therapy vs treatment
Mental state: specific – insight – average attitude to voices score (BAVQ‐R, high = poor) – short term · schizophrenia or related disorders
Avatar Therapy for people with schizophrenia or related disorders (2020) · Cochrane
no estimate extracted1 study · 19 participantsVery low
Avatar Therapy vs treatment
Global state: relapse (rehospitalised) – short term · schizophrenia or related disorders
Avatar Therapy for people with schizophrenia or related disorders (2020) · Cochrane
RD 01 study · 19 participantsLow