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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,956 questions in 143 reviews · Musculoskeletal

current versions
No studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions
Quality of life at discharge from hospital · acutely hospitalised older medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
no estimate extracted2 studies · 449 participantsModerate
Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions
Falls during hospitalisation · acutely hospitalised older medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
RR 0.96 [0.48, 1.91]5 studies · 995 participantsLow
Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions
Medical deterioration during hospitalisation · acutely hospitalised older medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
RR 0.99 [0.52, 1.87]7 studies · 1798 participantsVery low
Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions
Participant global assessment of success · acutely hospitalised older medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Summary of findings table ‐ Exercise interventions vs usual care with or without sham interventions
Functional ability: new incidence of delirium during hospitalisation · acutely hospitalised medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
RR 0.9 [0.58, 1.41]7 studies · 2088 participantsVery low
Summary of findings table ‐ Exercise interventions vs usual care with or without sham interventions
Quality of life at discharge from hospital · acutely hospitalised medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
no estimate extracted4 studies · 875 participantsLow
Summary of findings table ‐ Exercise interventions vs usual care with or without sham interventions
Falls during hospitalisation · acutely hospitalised medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
RR 0.99 [0.59, 1.65]9 studies · 1787 participantsModerate
Summary of findings table ‐ Exercise interventions vs usual care with or without sham interventions
Medical deterioration during hospitalisation · acutely hospitalised medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
RR 1.02 [0.62, 1.68]11 studies · 2730 participantsVery low
Summary of findings table ‐ Exercise interventions vs usual care with or without sham interventions
Participant global assessment of success · acutely hospitalised medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions
Functional ability: independence with activities of daily living at discharge from hospital · acutely hospitalised older medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
no estimate extracted4 studies · 2838 participantsLow
Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions
Functional ability: functional mobility at discharge from hospital · acutely hospitalised older medical patients
Exercise for acutely hospitalised older medical patients (2022) · Cochrane
no estimate extracted1 study · 975 participantsUngraded
Customised foot orthoses vs shoes
Pain (measured as proportion with pain) · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
RR 0.85 [0.67, 1.07]NRLow
Prefabricated foot orthoses vs shoes
Quality of life · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Prefabricated foot orthoses vs shoes
Treatment success · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Prefabricated foot orthoses vs shoes
Withdrawal due to adverse events · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
RR 0.99 [0.79, 1.23]NRVery low
Prefabricated foot orthoses vs shoes
Adverse events · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Prefabricated foot orthoses vs shoes
Serious adverse events · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs prefabricated foot orthoses
Pain(measured as proportion with pain) · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
RR 0.93 [0.73, 1.18]NRLow
Custom foot orthoses vs prefabricated foot orthoses
Function or disability · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs prefabricated foot orthoses
Quality of life · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs prefabricated foot orthoses
Treatment success · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs prefabricated foot orthoses
Withdrawal due to adverse events · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
RR 1 [0.9, 1.12]NRLow
Customised foot orthoses vs shoes
Function or disability · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs prefabricated foot orthoses
Adverse events · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs prefabricated foot orthoses
Serious adverse events · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs shoes
Pain(measured on 0 to 10‐point VAS; lower = less pain) · children with juvenile idiopathic arthritis (JIA) and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRVery low
Custom foot orthoses vs shoes
Function or disability (measured on 0 to 100‐point FFI; 0 = no disability) · children with juvenile idiopathic arthritis (JIA) and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Custom foot orthoses vs shoes
Quality of life (child‐rated) (measured on 0 to 100‐point PedsQL; higher score = better QoL) · children with juvenile idiopathic arthritis (JIA) and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Custom foot orthoses vs shoes
Quality of life (parent‐rated) (measured on 0 to 100‐point PedsQL; higher score = better QoL) · children with juvenile idiopathic arthritis (JIA) and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Custom foot orthoses vs shoes
Treatment success (measured on the 50FTW (seconds)) · children with juvenile idiopathic arthritis (JIA) and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Custom foot orthoses vs shoes
Withdrawal due to adverse events · children with juvenile idiopathic arthritis (JIA) and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
RR 0.58 [0.11, 2.94]NRLow
Custom foot orthoses vs shoes
Adverse events · children with juvenile idiopathic arthritis (JIA) and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs shoes
Serious adverse events · children with juvenile idiopathic arthritis (JIA) and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Customised foot orthoses vs shoes
Quality of life · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Prefabricated foot orthoses vs shoes
Pain(measured on 0 to 10‐point VAS; lower = less pain) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRVery low
Prefabricated foot orthoses vs shoes
Function or disability (measured on 0 to 100‐point FFI; 0 = no disability) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Prefabricated foot orthoses vs shoes
Quality of life (child‐rated) (measured on 0 to 100‐point PedsQL; higher score = better QoL) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Prefabricated foot orthoses vs shoes
Quality of life (parent‐rated) (measured on 0 to 100‐point PedsQL; higher score = better QoL) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Prefabricated foot orthoses vs shoes
Treatment success (measured on the 50FWT (seconds)) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Prefabricated foot orthoses vs shoes
Withdrawal due to adverse events · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
RR 0.72 [0.14, 3.61]NRUngraded
Prefabricated foot orthoses vs shoes
Adverse events · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Prefabricated foot orthoses vs shoes
Serious adverse events · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs prefabricated foot orthoses
Pain(measured on 0 to 10‐point VAS; lower = less pain) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Custom foot orthoses vs prefabricated foot orthoses
Function or disability (measured on 0 to 100‐point FFI; 0 = no disability) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Customised foot orthoses vs shoes
Treatment success · children with asymptomatic flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies
Custom foot orthoses vs prefabricated foot orthoses
Quality of life (child‐rated) (measured on 0 to 100‐point PedsQL; higher score = better QoL) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Custom foot orthoses vs prefabricated foot orthoses
Quality of life (parent‐rated) (measured on 0 to 100‐point PedsQL; higher score = better QoL) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Custom foot orthoses vs prefabricated foot orthoses
Treatment success (measured on the 50FWT (seconds)) · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRLow
Custom foot orthoses vs prefabricated foot orthoses
Withdrawal due to adverse events · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
RR 0.8 [0.13, 4.87]NRLow
Custom foot orthoses vs prefabricated foot orthoses
Adverse effects · children with juvenile idiopathic arthritis and flat feet
Foot orthoses for treating paediatric flat feet (2022) · Cochrane
no estimate extractedNRNo studies