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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,463 questions in 125 reviews · Anaesthesia
current versionsNo studies 197 · 13.5%Ungraded 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Ramosetron (no direct evidence, indirect evidence only) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR Tropisetron (3 RCTs; 187 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 3 studies · 187 participants | Very low |
Intervention NR D2 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 participants | Ungraded |
Intervention NR Amisulpride (1 RCT; 689 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 689 participants | Low |
Intervention NR Droperidol (22 RCTs; 3270 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 22 studies · 3270 participants | Low |
Intervention NR Haloperidol (5 RCTs; 437 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 5 studies · 437 participants | Low |
Intervention NR Metoclopramide (12 RCTs; 855 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 12 studies · 855 participants | Low |
Intervention NR Perphenazine (1 RCT; 115 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 115 participants | Very low |
Intervention NR NK1 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 participants | Ungraded |
Intervention NR Casopitant (no direct evidence, indirect evidence only) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | Low |
Intervention NR Aprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Casopitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Fosaprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Rolapitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Corticosteroids · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dexamethasone (4 RCTs; 1031 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 4 studies · 1031 participants | Low |
Intervention NR Methylprednisolone (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Antihistamines · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dimenhydrinate (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Meclizine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Fosaprepitant (No direct evidence, indirect evidence only) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | Moderate |
Intervention NR Promethazine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Anticholinergics · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Scopolamine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Comparator · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Placebo · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Total studies: 43 RCTs Total participants: 11,481 Number of treatments: 23 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 43 studies · 11481 participants | Ungraded |
Intervention NR Dolasetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Granisetron (3 RCTs; 230 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 3 studies · 230 participants | Very low |
Intervention NR Ondansetron (8 RCTs; 1475 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 8 studies · 1475 participants | Very low |
Intervention NR Palonosetron (3 RCTs; 1437 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 3 studies · 1437 participants | Very low |
Intervention NR Rolapitant (1 RCT; 515 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 515 participants | Very low |
Intervention NR Ramosetron (2 RCTs; 280 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 studies · 280 participants | Very low |
Intervention NR Tropisetron (2 RCTs; 226 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 studies · 226 participants | Very low |
Intervention NR D2 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 participants | Ungraded |
Intervention NR Amisulpride (2 RCTs; 904 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 studies · 904 participants | Very low |
Intervention NR Droperidol (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Haloperidol (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Metoclopramide (1 RCT; 80 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 80 participants | Low |
Intervention NR Perphenazine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR NK1 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 participants | Ungraded |
Intervention NR Aprepitant (no direct evidence, indirect evidence only) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR Corticosteroids · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Casopitant (no direct evidence, indirect evidence only) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR Fosaprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Rolapitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Corticosteroids · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dexamethasone (3 RCTs; 327 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 3 studies · 327 participants | Low |
Intervention NR Methylprednisolone (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Antihistamines · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |