Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,262 questions · 2,405 findings · 248 reviews · Headline outcomes only

No studies found 507 · 21.1%GRADE not reported 93 · 3.9%Very low 657 · 27.3%Low 708 · 29.4%Moderate 387 · 16.1%High 53 · 2.2%

Remote monitoring plus usual care vs usual care

Time to first hospitalisation after starting intervention · patients with chronic obstructive pulmonary disease

It is very uncertain whether remote monitoring plus usual care changes time to first hospitalisation after starting intervention compared with usual care (very low certainty).

1 finding from 1 review

Remote monitoring plus usual care vs usual care

Time to first COPD‐related re‐admission · patients with chronic obstructive pulmonary disease

Remote monitoring plus usual care probably leads to lower time to first COPD‐related re‐admission compared with usual care (moderate certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care showed no clear difference in self‐reported depressive symptoms short term (up to 6 months) ‐ BDI… compared with usual care alone (moderate certainty).

8 findings from 1 review
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Psychotherapy as an adjunct to usual care vs usual care

Dropout · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care showed no clear difference in dropout medium term (7 to 12 months)* compared with usual care alone (moderate certainty).

2 findings from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Response (50% reduction in BDI) medium term (7 to 12 months)* · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) medium term (7 to 12 months)* compared with usual care alone (low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Response (50% reduction in BDI) long term (longer than 12 months)* · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) long term (longer than 12 months)* compared with usual care alone (low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Remission · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care probably leads to higher remission (< 7 on HAMD or < 10 on BDI) medium term (7 to 12 months)* compared with usual care alone (moderate certainty).

2 findings from 1 review

Psychotherapy as an adjunct to usual care vs usual care

> 50% reduction in depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in depressive symptoms from baseline) short… compared with usual care alone (low certainty).

1 finding from 1 review

Glucocorticoid with cyclophosphamide plus usual care vs placebo or usual care

All‐cause mortality at final · people with moderate to severe oral paraquat poisoning

Glucocorticoid with cyclophosphamide plus usual care may leads to lower all‐cause mortality at final compared with usual care (with or without placebo) (low certainty).

2 findings from 1 review

Glucocorticoid with cyclophosphamide plus usual care vs placebo or usual care

New infection within 1 week after initiation of treatment Assessed through clinical diagnosis · people with moderate to severe oral paraquat poisoning

It is very uncertain whether glucocorticoid with cyclophosphamide plus usual care changes new infection within 1 week after initiation of treatment Assessed… compared with usual care (with or without placebo) (very low certainty).

1 finding from 1 review