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What do systematic reviews say?

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Evidence found and GRADE certainty

66 questions · 68 findings · 7 reviews

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No studies found 34 · 50%GRADE not reported 0 · 0%Very low 23 · 33.8%Low 8 · 11.8%Moderate 3 · 4.4%High 0 · 0%

Iodine vs topical antibiotics

Wound healing · people with burns

It is very uncertain whether iodine changes wound healing (mean time to healing) compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    2 studies · 148 participants
    Very low

Iodine vs topical antibiotics

Infection · people with burns

The review found no eligible studies for this question.

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Iodine vs topical antibiotics

Adverse events · people with burns

It is very uncertain whether iodine changes adverse events compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.86 [0.35, 2.1]
    1 study · 40 participants
    Very low

Honey vs topical antibiotics

Time to complete healing · people with burns

Honey probably leads to higher wound healing: time to complete healing (time‐to‐event data): honey… compared with topical antibiotics (moderate certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    HR 2.45 [1.71, 3.52]
    5 studies · 580 participants
    Moderate

Honey vs topical antibiotics

Wound healing · people with burns

It is very uncertain whether honey changes wound healing (mean time to healing): honey versus SSD compared with topical antibiotics (very low certainty).

2 findings from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    6 studies · 712 participants
    Very low
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 2.18 [1.15, 4.13]
    4 studies · 318 participants
    Low

Honey vs topical antibiotics

Incident infection: honey versus SSD or mafenide acetate · people with burns

It is very uncertain whether honey changes incident infection: honey versus SSD or mafenide acetate compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.16 [0.08, 0.34]
    4 studies · 480 participants
    Very low