Findings

What do systematic reviews say?

113 questions · 119 findings · 12 reviews · Urology

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No studies found 38 · 31.9%GRADE not reported 0 · 0%Very low 43 · 36.1%Low 21 · 17.6%Moderate 16 · 13.4%High 1 · 0.8%

Injectional verapamil vs saline (short‐term)

Degree of penile curvature · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Injectional verapamil vs saline (short‐term)

Treatment discontinuation · men with Peyronie's disease (palpable plaque or pain)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional Botox vs placebo

Outcomes ( · men with Peyronie's disease (stable phase)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional Botox vs placebo

Patient‐reported ability to have intercourse · men with Peyronie's disease (stable phase)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional Botox vs placebo

Quality of life · men with Peyronie's disease (stable phase)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Injectional Botox vs placebo

Treatment‐related adverse effects · men with Peyronie's disease (stable phase)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional Botox vs placebo

Degree of penile curvature · men with Peyronie's disease (stable phase)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional Botox vs placebo

Treatment discontinuation · men with Peyronie's disease (stable phase)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Extracorporeal shockwave therapy vs sham

Outcomes ( · men with Peyronie's disease (palpable plaque or pain)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Potassium paraaminobenzoate vs placebo

Degree of penile curvature · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Extracorporeal shockwave therapy vs sham

Patient‐reported ability to have intercourse · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether extracorporeal shock wave treatment (ESWT) changes patient‐reported ability to have intercourse compared with sham (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 1.6 [0.71, 3.6]
1 study · 26 participants
Very low

Extracorporeal shockwave therapy vs sham

Quality of life · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 130 participants
Low

Extracorporeal shockwave therapy vs sham

Treatment‐related adverse effects · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether extracorporeal shock wave treatment (ESWT) changes treatment‐related adverse effects compared with sham (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 2.73 [0.74, 10.14]
3 studies · 166 participants
Very low

Extracorporeal shockwave therapy vs sham

Degree of penile curvature · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 166 participants
Low

Extracorporeal shockwave therapy vs sham

Treatment discontinuation · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether extracorporeal shock wave treatment (ESWT) changes discontinuation from treatment compared with sham (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 0.57 [0.06, 5.65]
4 studies · 238 participants
Very low

Penile traction therapy vs no treatment (short‐term)

Outcomes ( · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Penile traction therapy vs no treatment (short‐term)

Patient‐reported ability to have intercourse · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Penile traction therapy vs no treatment (short‐term)

Quality of life · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 82 participants
Very low

Penile traction therapy vs no treatment (short‐term)

Treatment‐related adverse effects · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Very low

Penile traction therapy vs no treatment (short‐term)

Degree of penile curvature · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 89 participants
Very low