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Evidence found and GRADE certainty

67 questions · 67 findings · 3 reviews · Pain, Palliative and Supportive Care

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No studies found 44 · 65.7%GRADE not reported 1 · 1.5%Very low 8 · 11.9%Low 12 · 17.9%Moderate 1 · 1.5%High 1 · 1.5%

Summary of findings table ‐ Kappa‐opioid agonists vs placebo

Risk for at least one adverse drug reaction (ADR) per participant · patients with chronic kidney disease (CKD) pruritus

Summary of findings table ‐ Kappa‐opioid agonists may leads to higher risk for at least one adverse drug reaction (ADR) per patient compared with placebo (low certainty).

1 finding from 1 review