Findings

What do systematic reviews say?

873 questions · 883 findings · 38 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 319 · 36.1%GRADE not reported 18 · 2%Very low 198 · 22.4%Low 186 · 21.1%Moderate 147 · 16.6%High 15 · 1.7%

Summary of findings: ACBT vs exercise

FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Summary of findings: ACBT vs exercise

FVC (% predicted) Change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Summary of findings: ACBT vs exercise

Sputum weight (change from baseline) · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ACBT vs exercise

Pulmonary exacerbations · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Very low

Summary of findings: ACBT vs CCPT

FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
GRADE not reported

Summary of findings: ACBT vs CCPT

FVC (% predicted) Change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
GRADE not reported

Summary of findings: ACBT vs CCPT

Sputum weight (change from baseline) · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ACBT vs CCPT

Pulmonary exacerbations · adults and children with cystic fibrosis

Summary of findings: ACBT showed no clear difference in number of pulmonary exacerbations compared with CCPT (low certainty).

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
RR 1.64 [0.62, 4.34]
1 study · 63 participants
Low

Summary of findings: ACBT vs PEP mask therapy

Quality of life (change from baseline) in SF‐36 score and CRQ score · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Summary of findings: ACBT vs PEP mask therapy

Personal preference · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ PEP vs PDPV

FEV1 % predicted: absolute change from baseline · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 155 participants
Low

Summary of findings ‐ PEP vs oscillating PEP

Direct measures of mucus clearance · adults and children with CF

The review found no eligible studies for this question.

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ PEP vs oscillating PEP

Exercise capacity · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 68 participants
Moderate

Summary of findings ‐ PEP vs oscillating PEP

General well‐being · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 75 participants
Low

Summary of findings ‐ PEP vs oscillating PEP

LCI · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low

Summary of findings ‐ PEP vs oscillating PEP

Adverse events · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
22 participants
Low

Summary of findings ‐ PEP vs HFCWO

FEV1 % predicted: absolute change from baseline · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 174 participants
Low

Summary of findings ‐ PEP vs HFCWO

Pulmonary exacerbations · adults and children with CF

Summary of findings ‐ PEP leads to lower number of respiratory exacerbations compared with HFCWO (high certainty).

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
RR 0.73 [0.55, 0.95]
1 study · 107 participants
High

Summary of findings ‐ PEP vs HFCWO

Direct measures of mucus clearance · adults and children with CF

The review found no eligible studies for this question.

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ PEP vs HFCWO

Exercise capacity · adults and children with CF

The review found no eligible studies for this question.

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found