Findings

What do systematic reviews say?

69 questions · 69 findings · 16 reviews · Heart

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No studies found 12 · 17.4%GRADE not reported 1 · 1.4%Very low 10 · 14.5%Low 22 · 31.9%Moderate 20 · 29%High 4 · 5.8%

Intervention not reported

months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐ raised inflammatory markers)

The intervention probably leads to lower months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐… (moderate certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 0.41 [0.28, 0.61]
2 studies · 360 participants
Moderate

Intervention not reported

Symptom relief at 72 hours Patient reported

The intervention may leads to higher symptom relief at 72 hours Patient reported (low certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 1.4 [1.26, 1.56]
4 studies · 564 participants
Low

Intervention not reported

Total adverse effects Patient reported

The intervention showed no clear difference in total adverse effects Patient reported (low certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 1.26 [0.75, 2.12]
4 studies · 564 participants
Low

Intervention not reported

Adverse effects necessitating stop of therapy Patient reported

The intervention probably leads to higher adverse effects necessitating stop of therapy Patient reported (moderate certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 1.87 [1.02, 3.41]
4 studies · 564 participants
Moderate

Intervention not reported

months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐ raised inflammatory markers)

The intervention probably leads to lower months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐… (moderate certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 0.28 [0.17, 0.47]
2 studies · 204 participants
Moderate

Intervention not reported

months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐ raised inflammatory markers)

The intervention probably leads to lower months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐… (moderate certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 0.36 [0.23, 0.56]
2 studies · 204 participants
Moderate

Intervention not reported

months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐ raised inflammatory markers)

The intervention probably leads to lower months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐… (moderate certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 0.38 [0.25, 0.58]
2 studies · 204 participants
Moderate

Intervention not reported

months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐ raised inflammatory markers)

The intervention probably leads to lower months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐… (moderate certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 0.36 [0.23, 0.58]
2 studies · 360 participants
Moderate

Intervention not reported

months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐ raised inflammatory markers)

The intervention probably leads to lower months Chest pain + (ECG changes +/‐ echocardiographic changes +/‐… (moderate certainty).

1 finding from 1 review

Colchicine for pericarditis 2014 · Cochrane Headline outcomes only
RR 0.4 [0.26, 0.61]
2 studies · 360 participants
Moderate