Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

304 questions · 332 findings · 36 reviews · Headline outcomes only

No studies found 58 · 17.5%GRADE not reported 15 · 4.5%Very low 104 · 31.3%Low 110 · 33.1%Moderate 44 · 13.3%High 1 · 0.3%

Psychological therapy vs enhanced or structured care

Secondary outcome: acceptability of treatment · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy showed no clear difference in acceptability 1 ‐ proportion of participants withdrawing during… compared with enhanced or structured care (moderate certainty).

1 finding from 1 review

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke
2 findings from 1 review

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke
1 finding from 1 review