Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

71 questions · 74 findings · 27 reviews · Headline outcomes only

No studies found 3 · 4.1%GRADE not reported 4 · 5.4%Very low 5 · 6.8%Low 30 · 40.5%Moderate 22 · 29.7%High 10 · 13.5%

Magnesium sulphate vs placebo (outcomes

Death (fetal, neonatal, or later (up to school age))** · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death (fetal, neonatal, or later (up to school age))** compared with placebo (outcomes (low certainty).

1 finding from 1 review

Intervention not reported

Invasive infection prior to hospital discharge · very preterm (< 32 weeks' gestation) or very low birth weight (< 1500 g) infants

The intervention probably leads to higher invasive infection prior to hospital discharge (moderate certainty).

1 finding from 1 review