Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

163 questions · 166 findings · 9 reviews

No studies found 65 · 39.2%GRADE not reported 18 · 10.8%Very low 70 · 42.2%Low 12 · 7.2%Moderate 0 · 0%High 1 · 0.6%

Prebiotic vs placebo

Withdrawals due to adverse events · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)

It is very uncertain whether prebiotics changes withdrawals due to adverse events (14 days to 2 or 3 months) compared with placebo (very low certainty).

1 finding from 1 review

Prebiotic vs no prebiotics

Incidence of hyperbilirubinaemia · Neonates, including term neonates (gestational age ≥ 37 weeks), late preterm neonates (35 to 37 weeks' gestation) and preterm neonates (<…

Feeding supplementation with prebiotics may leads to lower incidence of hyperbilirubinaemia compared with no prebiotics (low certainty).

1 finding from 1 review

Prebiotic vs no prebiotics

Treatment with phototherapy · Neonates, including term neonates (gestational age ≥ 37 weeks), late preterm neonates (35 to 37 weeks' gestation) and preterm neonates (<…

Feeding supplementation with prebiotics may leads to lower treatment with phototherapy compared with no prebiotics (low certainty).

1 finding from 1 review