Incidence of dementia · Older people living in the community
Multi‐domain interventions showed no clear difference in incidence of dementia compared with usual care/placebo (high certainty).
1 finding from 1 review
Incidence of MCI · Older people living in the community
Multi‐domain interventions showed no clear difference in incidence of MCI compared with usual care/placebo (moderate certainty).
1 finding from 1 review
Cognitive decline · Older people living in the community
3 findings from 1 review
no estimate extracted
3 studies · 4617 participants
High
no estimate extracted
6 studies · 8697 participants
Moderate
no estimate extracted
2 studies · 1554 participants
Very low
All‐cause mortality · Older people living in the community
Multi‐domain interventions showed no clear difference in mortality compared with usual care/placebo (high certainty).
1 finding from 1 review
Specific behaviour ‐ agitation · people with dementia
1 finding from 1 review
Behavioural and psychological symptoms · people with dementia
1 finding from 1 review
Adverse effects · people with dementia
1 finding from 1 review
Quality of life · people with dementia
1 finding from 1 review
Mood · people with dementia
1 finding from 1 review
Sleep · people with dementia
1 finding from 1 review
Activities of daily living · people with dementia
1 finding from 1 review
Total nocturnal sleep time (minutes) · sleep disturbances in dementia
1 finding from 1 review
Number of nocturnal awakenings · sleep disturbances in dementia
1 finding from 1 review
Number of participants reporting an adverse event · sleep disturbances in dementia
Trazodone showed no clear difference in reporting ≥ 1 adverse event compared with placebo (low certainty).
1 finding from 1 review
Cognitive function · sleep disturbances in dementia
1 finding from 1 review
Quality of life · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Carer burden, well‐being or quality of life · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change from baseline in total nocturnal sleep time · sleep disturbances in dementia
1 finding from 1 review
Consolidated sleep time · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change from baseline in ratio of number of nocturnal awakenings to total sleep time × 100 · sleep disturbances in dementia
1 finding from 1 review