Findings

What do systematic reviews say?

70 questions · 70 findings · 6 reviews

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No studies found 29 · 41.4%GRADE not reported 1 · 1.4%Very low 15 · 21.4%Low 12 · 17.1%Moderate 11 · 15.7%High 2 · 2.9%

Corticosteroids vs control

Ventilator‐free days up to day 28 · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 494 participants
Low

Adverse events Defined as leading to discontinuation of study medication; or for studies with standard care control, defined by study authors as "serious adverse events" · adults with acute respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Corticosteroids vs control

Fitness to return to work at 12 months · adults with acute respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Surfactants vs control

Early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90 days. Time point not reported in 4 studies · adults with acute respiratory distress syndrome

It is very uncertain whether surfactants changes early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90… compared with control (very low certainty).

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 1.08 [0.91, 1.29]
9 studies · 1338 participants
Very low

Surfactants vs control

Late all‐cause mortality ( > 3 months · adults with acute respiratory distress syndrome

It is very uncertain whether surfactants changes late all‐cause mortality ( > 3 months) Reported at: 180 days compared with control (very low certainty).

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 1.28 [1.01, 1.61]
1 study · 418 participants
Very low

Surfactants vs control

Duration of mechanical ventilation · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Intervention not reported

Arrhythmias ‐ by drug type in all patients · Adult patients 18 years and above undergoing elective surgery

1 finding from 1 review

Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
no estimate extracted
57 studies · 2902 participants
Moderate

Intervention not reported

Arrhythmias ‐ high risk patients · Adult patients 18 years and above undergoing elective surgery

1 finding from 1 review

Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 337 participants
Moderate

Intervention not reported

Myocardial Ischaemia ‐ by drug type in all patients · Adult patients 18 years and above undergoing elective surgery

1 finding from 1 review

Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
no estimate extracted
30 studies · 1636 participants
Low

Intervention not reported

Myocardial Ischaemia ‐ high risk patients · Adult patients 18 years and above undergoing elective surgery

1 finding from 1 review

Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 395 participants
Moderate