Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

138 questions · 141 findings · 21 reviews

No studies found 34 · 24.1%GRADE not reported 7 · 5%Very low 44 · 31.2%Low 33 · 23.4%Moderate 13 · 9.2%High 10 · 7.1%

RISPERIDONE vs OLANZAPINE

Global outcome: need for additional measures · psychosis‐induced aggression or agitation (rapid tranquillisation)

It is very uncertain whether RISPERIDONE changes global outcome: need for additional measures compared with OTHER ANTIPSYCHOTIC: b. OLANZAPINE (very low certainty).

1 finding from 1 review

RISPERIDONE vs OLANZAPINE

Leaving the study early · people with both severe mental illness and substance misuse

It is very uncertain whether RISPERIDONE changes leaving study early: any reason compared with OLANZAPINE ‒ short‐ and long‐term data (very low certainty).

1 finding from 1 review